Msm and Back pain - a phase IV clinical study of FDA data

Summary:

Back pain is reported as a side effect among people who take Msm (methylsulfonylmethane), especially for people who are female, 60+ old, have been taking the drug for 10+ years also take Proair Hfa, and have Systemic lupus erythematosus.

The phase IV clinical study analyzes which people have Back pain when taking Msm. It is created by eHealthMe based on reports of 978 people who have side effects when taking Msm from the FDA, and is updated regularly.

What is Msm?

Msm has active ingredients of methylsulfonylmethane. It is often used in joint pain. eHealthMe is studying from 1,210 Msm users. Check the latest studies of Msm.

What is Back pain?

Back pain is found to be associated with 3,220 drugs and 4,710 conditions by eHealthMe. Check the latest studies of Back pain.

On Jul, 08, 2026

978 people reported to have side effects when taking Msm.
Among them, 23 people (2.35%) have Back pain.

Among these 23 people:

How long have people been on Msm when they have Back pain? *

What is the gender of people who have Back pain when taking Msm? *

female: 86.96 %
male: 13.04 %

What is the age of people who have Back pain when taking Msm? *

What are other drugs people take besides Msm? *

What are other side effects people have besides Back pain? *

Weakness: 10 people, 43.48%
Headache (pain in head): 8 people, 34.78%
Dyspnea (difficult or laboured breathing): 5 people, 21.74%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 21.74%
Nausea (feeling of having an urge to vomit): 5 people, 21.74%
Pain: 5 people, 21.74%
Fatigue (feeling of tiredness): 5 people, 21.74%
Hypoaesthesia (reduced sense of touch or sensation): 5 people, 21.74%
Joint Swelling: 5 people, 21.74%
Fall: 4 people, 17.39%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 17.39%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 4 people, 17.39%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 17.39%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 8.70%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 8.70%
Osteoporosis (bones weak and more likely to break): 2 people, 8.70%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 8.70%
High Blood Cholesterol: 2 people, 8.70%
Urinary Tract Infection: 1 person, 4.35%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Msm and have Back pain?

- Check whether Back pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Msm:

Msm (1,210 reports)

Back pain treatments and more:

Back pain (379,875 reports)

Browse all side effects of Msm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Back pain:

Back pain (3,220 drugs)

Browse all the conditions that are associated with Back pain:

Back pain (4,710 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylsulfonylmethane (the active ingredients of Msm) and Msm (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.