Mucinex d and Weight increased - a phase IV clinical study of FDA data

Summary:

Weight increased is reported as a side effect among people who take Mucinex d (guaifenesin; pseudoephedrine hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Singulair, and have Narcolepsy.

The phase IV clinical study analyzes which people have Weight increased when taking Mucinex d. It is created by eHealthMe based on reports of 1,430 people who have side effects when taking Mucinex d from the FDA, and is updated regularly.

What is Mucinex d?

Mucinex d has active ingredients of guaifenesin; pseudoephedrine hydrochloride. It is often used in sinus congestion. eHealthMe is studying from 1,926 Mucinex d users. Check the latest studies of Mucinex d.

What is Weight increased?

Weight increased is found to be associated with 2,889 drugs and 3,962 conditions by eHealthMe. Check the latest studies of Weight increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

1,430 people reported to have side effects when taking Mucinex d.
Among them, 24 people (1.68%) have Weight increased.

Could Mucinex d cause Weight increased?

Among these 24 people:

How long have people been on Mucinex d when they have Weight increased? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Weight increased when taking Mucinex d? *

  • female: 79.17 %
  • male: 20.83 %

What is the age of people who have Weight increased when taking Mucinex d? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 14.29 %
  • 20-29: 0.0 %
  • 30-39: 7.14 %
  • 40-49: 21.43 %
  • 50-59: 35.71 %
  • 60+: 21.43 %

What are other drugs people take besides Mucinex d? *

  1. Singulair: 11 people, 45.83%
  2. Claritin: 8 people, 33.33%
  3. Magnesium: 8 people, 33.33%
  4. Epinephrine: 7 people, 29.17%
  5. Nexium: 7 people, 29.17%
  6. Zyrtec: 7 people, 29.17%
  7. Acetaminophen: 7 people, 29.17%
  8. Xyrem: 6 people, 25.00%
  9. Lidocaine: 6 people, 25.00%
  10. Sodium Chloride: 5 people, 20.83%

What are other side effects people have besides Weight increased? *

  1. Headache (pain in head): 8 people, 33.33%
  2. Pneumonia: 7 people, 29.17%
  3. Rashes (redness): 7 people, 29.17%
  4. Skin Discoloration: 7 people, 29.17%
  5. Fatigue (feeling of tiredness): 7 people, 29.17%
  6. Abdominal Distension: 6 people, 25.00%
  7. Dyspnea (difficult or laboured breathing): 6 people, 25.00%
  8. Productive Cough: 6 people, 25.00%
  9. Infection: 6 people, 25.00%
  10. Seasonal Allergy (allergic condition due to certain season): 6 people, 25.00%

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 25.00%
  2. Primary Immunodeficiency Syndrome: 4 people, 16.67%
  3. Immunodeficiency Common Variable: 4 people, 16.67%
  4. Multiple Myeloma (cancer of the plasma cells): 3 people, 12.50%
  5. Hypersensitivity: 3 people, 12.50%
  6. Pain: 3 people, 12.50%
  7. Migraine (headache): 3 people, 12.50%
  8. Depression: 2 people, 8.33%
  9. Drowsiness: 2 people, 8.33%
  10. High Blood Cholesterol: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Mucinex d and have Weight increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mucinex d:

Weight increased treatments and more:

How severe was Weight increased and when was it recovered:

Expand to all the drugs that have ingredients of guaifenesin; pseudoephedrine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mucinex d:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weight increased:

Browse all the conditions that are associated with Weight increased:


How the study uses the data?

The study uses data from the FDA. It is based on guaifenesin; pseudoephedrine hydrochloride (the active ingredients of Mucinex d) and Mucinex d (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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