Mucinex and Injection site swelling - a phase IV clinical study of FDA data

Summary:

Injection site swelling is reported as a side effect among people who take Mucinex (guaifenesin), especially for people who are female, 60+ old, also take Epinephrine, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Injection site swelling when taking Mucinex. It is created by eHealthMe based on reports of 28,090 people who have side effects when taking Mucinex from the FDA, and is updated regularly.

What is Mucinex?

Mucinex has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 29,749 Mucinex users. Check the latest studies of Mucinex.

What is Injection site swelling?

Injection site swelling is found to be associated with 1,057 drugs and 1,115 conditions by eHealthMe. Check the latest studies of Injection site swelling.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

28,090 people reported to have side effects when taking Mucinex.
Among them, 67 people (0.24%) have Injection site swelling.

Could Mucinex cause Injection site swelling?

Among these 67 people:

What is the gender of people who have Injection site swelling when taking Mucinex? *

female: 74.24 %
male: 25.76 %

What is the age of people who have Injection site swelling when taking Mucinex? *

What are other drugs people take besides Mucinex? *

What are other side effects people have besides Injection site swelling? *

Injection Site Pain: 31 people, 46.27%
Injection Site Erythema (redness at injection site): 30 people, 44.78%
Sinusitis (inflammation of sinus): 20 people, 29.85%
Dizziness: 19 people, 28.36%
Urinary Tract Infection: 18 people, 26.87%
Injection Site Pruritus (severe itching at injection site): 18 people, 26.87%
Rashes (redness): 14 people, 20.90%
Injection Site Reaction: 14 people, 20.90%
Urticaria (rash of round, red welts on the skin that itch intensely): 13 people, 19.40%
Fatigue (feeling of tiredness): 12 people, 17.91%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 37 people, 55.22%
Urticaria (rash of round, red welts on the skin that itch intensely): 8 people, 11.94%
B-Lymphocyte Abnormalities (abnormal population of b lymphocytes in the blood, bone marrow, or tissues): 7 people, 10.45%
Asthma: 6 people, 8.96%
Seasonal Allergy (allergic condition due to certain season): 3 people, 4.48%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 4.48%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 4.48%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 4.48%
Pneumonia: 2 people, 2.99%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 1.49%

* Approximation only. Some reports may have incomplete information.

Do you take Mucinex and have Injection site swelling?

- Check whether Injection site swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mucinex:

Mucinex (29,749 reports)

Browse all side effects of Mucinex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site swelling:

Injection site swelling (1,057 drugs)

Browse all the conditions that are associated with Injection site swelling:

Injection site swelling (1,115 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on guaifenesin (the active ingredients of Mucinex) and Mucinex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.