Nac and Diarrhea - a phase IV clinical study of FDA data

Summary:

Diarrhea is reported as a side effect among people who take Nac (n - acetyl cysteine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Vitamin D3, and have Idiopathic pulmonary fibrosis.

The phase IV clinical study analyzes which people have Diarrhea when taking Nac. It is created by eHealthMe based on reports of 626 people who have side effects when taking Nac from the FDA, and is updated regularly.

What is Nac?

Nac has active ingredients of n - acetyl cysteine. eHealthMe is studying from 855 Nac users. Check the latest studies of Nac.

What is Diarrhea?

Diarrhea is found to be associated with 3,732 drugs and 5,750 conditions by eHealthMe. Check the latest studies of Diarrhea.

On Apr, 16, 2026

626 people reported to have side effects when taking Nac.
Among them, 57 people (9.11%) have Diarrhea.

Among these 57 people:

How long have people been on Nac when they have Diarrhea? *

What is the gender of people who have Diarrhea when taking Nac? *

female: 48.21 %
male: 51.79 %

What is the age of people who have Diarrhea when taking Nac? *

What are other drugs people take besides Nac? *

What are other side effects people have besides Diarrhea? *

Nausea (feeling of having an urge to vomit): 21 people, 36.84%
Fatigue (feeling of tiredness): 17 people, 29.82%
Pain: 15 people, 26.32%
Headache (pain in head): 14 people, 24.56%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 14 people, 24.56%
Weakness: 13 people, 22.81%
Urinary Tract Infection: 12 people, 21.05%
Dyspnea (difficult or laboured breathing): 12 people, 21.05%
Dizziness: 11 people, 19.30%
Weight Decreased: 10 people, 17.54%

What are the existing conditions these people have? *

Idiopathic Pulmonary Fibrosis (chronic lung disease): 17 people, 29.82%
Immunodeficiency Common Variable: 6 people, 10.53%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 8.77%
Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 3 people, 5.26%
Constipation: 3 people, 5.26%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 3 people, 5.26%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 3 people, 5.26%
Amyotrophic Lateral Sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord): 2 people, 3.51%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 3.51%
Pain: 2 people, 3.51%

* Approximation only. Some reports may have incomplete information.

Do you take Nac and have Diarrhea?

- Check whether Diarrhea is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nac:

Nac (855 reports)

Diarrhea treatments and more:

Diarrhea (756,290 reports)

Browse all side effects of Nac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diarrhea:

Diarrhea (3,732 drugs)

Browse all the conditions that are associated with Diarrhea:

Diarrhea (5,750 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on n - acetyl cysteine (the active ingredients of Nac) and Nac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.