Naprelan and Weakness - a phase IV clinical study of FDA data

Summary:

Weakness is reported as a side effect among people who take Naprelan (naproxen sodium), especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months also take Zometa, and have Arthritis.

The phase IV clinical study analyzes which people have Weakness when taking Naprelan. It is created by eHealthMe based on reports of 687 people who have side effects when taking Naprelan from the FDA, and is updated regularly.

What is Naprelan?

Naprelan has active ingredients of naproxen sodium. eHealthMe is studying from 731 Naprelan users. Check the latest studies of Naprelan.

What is Weakness?

Weakness is found to be associated with 3,638 drugs and 6,617 conditions by eHealthMe. Check the latest studies of Weakness.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Jul, 17, 2026

687 people reported to have side effects when taking Naprelan.
Among them, 33 people (4.8%) have Weakness.

Could Naprelan cause Weakness?

Among these 33 people:

How long have people been on Naprelan when they have Weakness? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Weakness when taking Naprelan? *

  • female: 84.85 %
  • male: 15.15 %

What is the age of people who have Weakness when taking Naprelan? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 3.57 %
  • 20-29: 0.0 %
  • 30-39: 7.14 %
  • 40-49: 35.71 %
  • 50-59: 35.71 %
  • 60+: 17.86 %

What are other drugs people take besides Naprelan? *

  1. Zometa: 9 people, 27.27%
  2. Vicoprofen: 8 people, 24.24%
  3. Aredia: 8 people, 24.24%
  4. Colace: 8 people, 24.24%
  5. Compazine: 8 people, 24.24%
  6. Dexamethasone: 8 people, 24.24%
  7. Morphine Sulfate: 8 people, 24.24%
  8. Pepcid: 8 people, 24.24%
  9. Restoril: 8 people, 24.24%
  10. Lovenox: 8 people, 24.24%

What are other side effects people have besides Weakness? *

  1. Back Pain: 17 people, 51.52%
  2. Joint Pain: 16 people, 48.48%
  3. Fatigue (feeling of tiredness): 16 people, 48.48%
  4. Neck Pain: 14 people, 42.42%
  5. Cough: 12 people, 36.36%
  6. Oropharyngeal Pain: 11 people, 33.33%
  7. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 11 people, 33.33%
  8. Pain In Extremity: 10 people, 30.30%
  9. Headache (pain in head): 10 people, 30.30%
  10. Chest Pain: 9 people, 27.27%

What are the existing conditions these people have? *

  1. Arthritis (form of joint disorder that involves inflammation of one or more joints): 9 people, 27.27%
  2. Metastases To Bone (cancer spreads to bone): 8 people, 24.24%
  3. Psoriasis (immune-mediated disease that affects the skin): 5 people, 15.15%
  4. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 15.15%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.06%
  6. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 1 person, 3.03%
  7. Fatigue (feeling of tiredness): 1 person, 3.03%
  8. Breast Cancer: 1 person, 3.03%
  9. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 3.03%
  10. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Naprelan and have Weakness?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naprelan:

Weakness treatments and more:

How severe was Weakness and when was it recovered:

Expand to all the drugs that have ingredients of naproxen sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Naprelan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weakness:

Browse all the conditions that are associated with Weakness:


How the study uses the data?

The study uses data from the FDA. It is based on naproxen sodium (the active ingredients of Naprelan) and Naprelan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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