Narcan and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Narcan (naloxone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zofran, and have Pain.

The phase IV clinical study analyzes which people have Stroke when taking Narcan. It is created by eHealthMe based on reports of 3,672 people who have side effects when taking Narcan from the FDA, and is updated regularly.

What is Narcan?

Narcan has active ingredients of naloxone hydrochloride. eHealthMe is studying from 3,687 Narcan users. Check the latest studies of Narcan.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,350 drugs and 3,023 conditions by eHealthMe. Check the latest studies of Stroke.

On Apr, 06, 2026

3,672 people reported to have side effects when taking Narcan.
Among them, 42 people (1.14%) have Stroke.

Among these 42 people:

How long have people been on Narcan when they have Stroke? *

What is the gender of people who have Stroke when taking Narcan? *

female: 78.38 %
male: 21.62 %

What is the age of people who have Stroke when taking Narcan? *

What are other drugs people take besides Narcan? *

What are other side effects people have besides Stroke? *

Urinary Tract Infection: 12 people, 28.57%
Dyspnea (difficult or laboured breathing): 12 people, 28.57%
Pain: 12 people, 28.57%
Stress And Anxiety: 12 people, 28.57%
Depression: 10 people, 23.81%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 10 people, 23.81%
Weakness: 9 people, 21.43%
Injury: 9 people, 21.43%
Gait Disturbance: 8 people, 19.05%
Acute Kidney Failure: 7 people, 16.67%

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 14.29%
Pain: 6 people, 14.29%
Multiple Myeloma (cancer of the plasma cells): 4 people, 9.52%
Acne (skin problems that cause pimples): 3 people, 7.14%
Nausea (feeling of having an urge to vomit): 3 people, 7.14%
Birth Control: 3 people, 7.14%
Overdose: 3 people, 7.14%
Abdominal Infection: 2 people, 4.76%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 4.76%
Headache (pain in head): 2 people, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Narcan and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Narcan:

Narcan (3,687 reports)

Stroke treatments and more:

Stroke (334,634 reports)

Browse all side effects of Narcan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Stroke (2,350 drugs)

Browse all the conditions that are associated with Stroke:

Stroke (3,023 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on naloxone hydrochloride (the active ingredients of Narcan) and Narcan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.