Narcan and Systemic lupus erythematosus - a phase IV clinical study of FDA data

Summary:

Systemic lupus erythematosus is reported as a side effect among people who take Narcan (naloxone hydrochloride), especially for people who are female, 60+ old, also take Furosemide, and have High blood pressure.

The phase IV clinical study analyzes which people have Systemic lupus erythematosus when taking Narcan. It is created by eHealthMe based on reports of 3,672 people who have side effects when taking Narcan from the FDA, and is updated regularly.

What is Narcan?

Narcan has active ingredients of naloxone hydrochloride. eHealthMe is studying from 3,687 Narcan users. Check the latest studies of Narcan.

What is Systemic lupus erythematosus?

Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue) is found to be associated with 1,088 drugs and 1,643 conditions by eHealthMe. Check the latest studies of Systemic lupus erythematosus.

On Jul, 23, 2026

3,672 people reported to have side effects when taking Narcan.
Among them, 15 people (0.41%) have Systemic lupus erythematosus.

Could Narcan cause Systemic lupus erythematosus?

Among these 15 people:

What is the gender of people who have Systemic lupus erythematosus when taking Narcan? *

female: 100 %
male: 0.0 %

What is the age of people who have Systemic lupus erythematosus when taking Narcan? *

What are other drugs people take besides Narcan? *

What are other side effects people have besides Systemic lupus erythematosus? *

Nausea (feeling of having an urge to vomit): 8 people, 53.33%
Dizziness: 7 people, 46.67%
Fatigue (feeling of tiredness): 6 people, 40.00%
Hypotension (abnormally low blood pressure): 6 people, 40.00%
Anaemia (lack of blood): 5 people, 33.33%
Dehydration (dryness resulting from the removal of water): 5 people, 33.33%
Dyspnea (difficult or laboured breathing): 4 people, 26.67%
Malaise (a feeling of general discomfort or uneasiness): 4 people, 26.67%
Headache (pain in head): 4 people, 26.67%
Abdominal Distension: 4 people, 26.67%

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 33.33%
Stress And Anxiety: 4 people, 26.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 26.67%
Pain: 4 people, 26.67%
Sleep Disorder: 3 people, 20.00%
Depression: 3 people, 20.00%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 20.00%
Itching: 3 people, 20.00%
Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 2 people, 13.33%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

Do you take Narcan and have Systemic lupus erythematosus?

- Check whether Systemic lupus erythematosus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Narcan:

Narcan (3,687 reports)

Browse all side effects of Narcan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Systemic lupus erythematosus:

Systemic lupus erythematosus (1,088 drugs)

Browse all the conditions that are associated with Systemic lupus erythematosus:

Systemic lupus erythematosus (1,643 conditions)

Related publications that referenced our studies

Hania A, "Pyoderma Gangrenosum in a Patient With Systemic Lupus Erythematosus: Case Report", Journal of Medical Cases, 2014 Aug .
Hu P, Lu L, Hu B, Deng F, Fei WJ, "Cyclophosphamide‐Induced Hypertensive Encephalopathy in a Young Girl With Lupus", The Journal of Clinical Hypertension, 2012 Apr .
Hania A, "Pyoderma Gangrenosum in a Patient With Systemic Lupus Erythematosus: Case Report", Journal of Medical Cases, 2014 Aug .
Hu P, Lu L, Hu B, Deng F, Fei WJ, "Cyclophosphamide‐Induced Hypertensive Encephalopathy in a Young Girl With Lupus", The Journal of Clinical Hypertension, 2012 Apr .

How the study uses the data?

The study uses data from the FDA. It is based on naloxone hydrochloride (the active ingredients of Narcan) and Narcan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.