Nardil and Agitation - a phase IV clinical study of FDA data

Summary:

Agitation is reported as a side effect among people who take Nardil (phenelzine sulfate), especially for people who are female, 60+ old, have been taking the drug for 10+ years also take Alprazolam, and have Bipolar i disorder.

The phase IV clinical study analyzes which people have Agitation when taking Nardil. It is created by eHealthMe based on reports of 2,128 people who have side effects when taking Nardil from the FDA, and is updated regularly.

What is Nardil?

Nardil has active ingredients of phenelzine sulfate. It is often used in depression. eHealthMe is studying from 2,327 Nardil users. Check the latest studies of Nardil.

What is Agitation?

Agitation (state of anxiety or nervous excitement) is found to be associated with 2,281 drugs and 3,318 conditions by eHealthMe. Check the latest studies of Agitation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

2,128 people reported to have side effects when taking Nardil.
Among them, 63 people (2.96%) have Agitation.

Among these 63 people:

How long have people been on Nardil when they have Agitation? *

What is the gender of people who have Agitation when taking Nardil? *

female: 55 %
male: 45 %

What is the age of people who have Agitation when taking Nardil? *

What are other drugs people take besides Nardil? *

What are other side effects people have besides Agitation? *

Stress And Anxiety: 35 people, 55.56%
Fatigue (feeling of tiredness): 23 people, 36.51%
Dizziness: 21 people, 33.33%
Back Pain: 21 people, 33.33%
Drowsiness: 20 people, 31.75%
Dry Mouth: 20 people, 31.75%
Nervousness: 19 people, 30.16%
Weakness: 18 people, 28.57%
Gait Disturbance: 18 people, 28.57%
Confusional State: 18 people, 28.57%

What are the existing conditions these people have? *

Parkinson's Disease: 16 people, 25.40%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 16 people, 25.40%
Oesophageal Disorder (disease of oesophagus): 14 people, 22.22%
Panic Disorder: 12 people, 19.05%
Stress And Anxiety: 2 people, 3.17%
Urinary Tract Infection: 1 person, 1.59%
Thinking Abnormal: 1 person, 1.59%
Sedation: 1 person, 1.59%
Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 1.59%
Head Injury: 1 person, 1.59%

* Approximation only. Some reports may have incomplete information.

Do you take Nardil and have Agitation?

- Check whether Agitation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nardil:

Nardil (2,327 reports)

Agitation treatments and more:

Agitation (142,109 reports)

Browse all side effects of Nardil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Agitation:

Agitation (2,281 drugs)

Browse all the conditions that are associated with Agitation:

Agitation (3,318 conditions)

Related publications that referenced our studies

Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on phenelzine sulfate (the active ingredients of Nardil) and Nardil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.