Neoral and Diastolic dysfunction - a phase IV clinical study of FDA data

Summary:

Diastolic dysfunction is reported as a side effect among people who take Neoral (cyclosporine), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Mycostatin, and have High blood pressure.

The phase IV clinical study analyzes which people have Diastolic dysfunction when taking Neoral. It is created by eHealthMe based on reports of 25,970 people who have side effects when taking Neoral from the FDA, and is updated regularly.

What is Neoral?

Neoral has active ingredients of cyclosporine. It is often used in psoriasis. eHealthMe is studying from 26,084 Neoral users. Check the latest studies of Neoral.

What is Diastolic dysfunction?

Diastolic dysfunction is found to be associated with 685 drugs and 630 conditions by eHealthMe. Check the latest studies of Diastolic dysfunction.

On Jul, 10, 2026

25,970 people reported to have side effects when taking Neoral.
Among them, 14 people (0.05%) have Diastolic dysfunction.

Could Neoral cause Diastolic dysfunction?

Among these 14 people:

How long have people been on Neoral when they have Diastolic dysfunction? *

What is the gender of people who have Diastolic dysfunction when taking Neoral? *

female: 33.33 %
male: 66.67 %

What is the age of people who have Diastolic dysfunction when taking Neoral? *

What are other drugs people take besides Neoral? *

What are other side effects people have besides Diastolic dysfunction? *

Cardiac Failure: 4 people, 28.57%
Heart Transplant Rejection: 4 people, 28.57%
Oedema (fluid collection in tissue): 4 people, 28.57%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 21.43%
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 3 people, 21.43%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 21.43%
Fall: 3 people, 21.43%
Nausea And Vomiting: 3 people, 21.43%
Blood Creatinine Increased: 3 people, 21.43%
Sudden Cardiac Death: 3 people, 21.43%

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 28.57%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 21.43%
Cardiac Failure: 3 people, 21.43%
Aplastic Anemia: 3 people, 21.43%
Mucosal Inflammation (infection of mucous membrane): 2 people, 14.29%
Immunodeficiency Disorders: 2 people, 14.29%
Oral Candidiasis (fungal infection of mouth): 2 people, 14.29%
Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 2 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
Fever: 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Neoral and have Diastolic dysfunction?

- Check whether Diastolic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Neoral:

Neoral (26,084 reports)

Browse all side effects of Neoral:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diastolic dysfunction:

Diastolic dysfunction (685 drugs)

Browse all the conditions that are associated with Diastolic dysfunction:

Diastolic dysfunction (630 conditions)

Related publications that referenced our studies

O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine (the active ingredients of Neoral) and Neoral (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.