Ms contin and Evoxac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ms contin (morphine sulfate) and Evoxac (cevimeline hydrochloride). Common drug interactions include pain in jaw among females and disease progression among males.

The phase IV clinical study analyzes what interactions people have when they take Ms contin and Evoxac. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Ms contin?

Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.

What is Evoxac?

Evoxac has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 2,028 Evoxac users. Check the latest studies of Evoxac.



On Jul, 10, 2026

42 people who take Ms contin and Evoxac together, and have interactions are studied.

Ms contin and Evoxac drug interactions.

What are the common drug interactions of Ms Contin and Evoxac, by gender? *:

female:

  1. Pain in jaw
  2. Emotional distress
  3. Epistaxis (bleed from the nose)
  4. Eye infection
  5. Eye pain
  6. Facial bones fracture (bone fracture of face)
  7. Fall
  8. Femur fracture
  9. Glossitis (infection of tongue with soreness)
  10. Groin pain

male:

  1. Disease progression

What are the common drug interactions of Ms Contin and Evoxac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Disease progression

50-59:

  1. Dizziness
  2. Emotional distress
  3. Epistaxis (bleed from the nose)
  4. Eye infection
  5. Eye pain
  6. Facial bones fracture (bone fracture of face)
  7. Fall
  8. Femur fracture
  9. Glossitis (infection of tongue with soreness)
  10. Groin pain

60+:

  1. Injection site pain
  2. Abdominal pain
  3. Breast cancer recurrent
  4. Bruxism (habitual grinding of the teeth, typically during sleep)
  5. Cardiac failure congestive
  6. Carditis (infection of heart and surrounding)
  7. Cellulitis (infection under the skin)
  8. Chest pain
  9. Chest wall mass
  10. Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)

What are the existing conditions these people have? *

  1. Breast Cancer: 8 people, 19.05%
  2. Osteoporosis (bones weak and more likely to break): 5 people, 11.90%
  3. Multiple Myeloma (cancer of the plasma cells): 4 people, 9.52%
  4. Metastases To Bone (cancer spreads to bone): 4 people, 9.52%
  5. Depression: 4 people, 9.52%
  6. Immunodeficiency Common Variable: 3 people, 7.14%
  7. Dry Mouth: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Ms contin and Evoxac?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ms contin and Evoxac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Evoxac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ms contin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Evoxac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and cevimeline hydrochloride (the active ingredients of Ms contin and Evoxac, respectively), and Ms contin and Evoxac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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