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Theo-dur and Erythema multiforme - a phase IV clinical study of FDA data

Summary:

Erythema multiforme is reported as a side effect among people who take Theo-dur (theophylline), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Rocephin, and have Constipation.

The phase IV clinical study analyzes which people have Erythema multiforme when taking Theo-dur. It is created by eHealthMe based on reports of 4,432 people who have side effects when taking Theo-dur from the FDA, and is updated regularly.

What is Theo-dur?

Theo-dur has active ingredients of theophylline. It is often used in asthma. eHealthMe is studying from 4,451 Theo-dur users. Check the latest studies of Theo-dur.

What is Erythema multiforme?

Erythema multiforme (a type of hypersensitivity reaction) is found to be associated with 1,707 drugs and 2,920 conditions by eHealthMe. Check the latest studies of Erythema multiforme.

On Jul, 10, 2026

4,432 people reported to have side effects when taking Theo-dur.
Among them, 43 people (0.97%) have Erythema multiforme.

Could Theo-dur cause Erythema multiforme?

Among these 43 people:

How long have people been on Theo-dur when they have Erythema multiforme? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Erythema multiforme when taking Theo-dur? *

  • female: 53.49 %
  • male: 46.51 %

What is the age of people who have Erythema multiforme when taking Theo-dur? *

  • 0-1: 0.0 %
  • 2-9: 9.76 %
  • 10-19: 7.32 %
  • 20-29: 7.32 %
  • 30-39: 0.0 %
  • 40-49: 12.2 %
  • 50-59: 7.32 %
  • 60+: 56.1 %

What are other drugs people take besides Theo-dur? *

  1. Rocephin: 9 people, 20.93%
  2. Tamiflu: 8 people, 18.60%
  3. Singulair: 7 people, 16.28%
  4. Depakene: 4 people, 9.30%
  5. Minocycline Hydrochloride: 4 people, 9.30%
  6. Adalat: 4 people, 9.30%
  7. Zantac: 3 people, 6.98%
  8. Serevent: 3 people, 6.98%
  9. Lamictal: 3 people, 6.98%
  10. Intal: 3 people, 6.98%

What are other side effects people have besides Erythema multiforme? *

  1. Methicillin-Resistant Staphylococcal Aureus Infection: 4 people, 9.30%
  2. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 4 people, 9.30%
  3. Fever: 4 people, 9.30%
  4. Face Oedema (swelling of face): 3 people, 6.98%
  5. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 3 people, 6.98%
  6. Cardiac Arrest: 3 people, 6.98%
  7. Respiratory Distress (difficulty in breathing): 3 people, 6.98%
  8. Rashes (redness): 3 people, 6.98%
  9. Lymphocyte Stimulation Test Positive: 3 people, 6.98%
  10. Loss Of Consciousness: 2 people, 4.65%

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 3 people, 6.98%
  2. Constipation: 3 people, 6.98%
  3. Analgesic Asthma Syndrome (asthma caused by the use of pain-killing and anti-inflammatory drugs): 2 people, 4.65%
  4. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 4.65%
  5. Bipolar Disorder (mood disorder): 2 people, 4.65%
  6. Insomnia (sleeplessness): 2 people, 4.65%
  7. High Blood Pressure: 2 people, 4.65%
  8. Herpes Zoster: 2 people, 4.65%
  9. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 2 people, 4.65%
  10. Gastric Ulcer (stomach ulcer): 2 people, 4.65%

* Approximation only. Some reports may have incomplete information.

Do you take Theo-dur and have Erythema multiforme?

- Check whether Erythema multiforme is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Theo-dur:

Erythema multiforme treatments and more:

How severe was Erythema multiforme and when was it recovered:

Expand to all the drugs that have ingredients of theophylline:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Theo-dur:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Erythema multiforme:

Browse all the conditions that are associated with Erythema multiforme:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on theophylline (the active ingredients of Theo-dur) and Theo-dur (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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