Zithromax and Definity drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zithromax (azithromycin) and Definity (perflutren). Common drug interactions include dyspnoea among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Zithromax and Definity. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Zithromax?

Zithromax has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 35,525 Zithromax users. Check the latest studies of Zithromax.

What is Definity?

Definity has active ingredients of perflutren. eHealthMe is studying from 4,853 Definity users. Check the latest studies of Definity.

On Jul, 10, 2026

19 people who take Zithromax and Definity together, and have interactions are studied.

Zithromax and Definity drug interactions.

What are the common drug interactions of Zithromax and Definity, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Loss of consciousness
Abnormal behaviour
Acute respiratory failure
Agitation (state of anxiety or nervous excitement)
Anaphylactic reaction (serious allergic reaction)
Aphasia (damage to the parts of the brain that control language)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

male:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Pleural effusion (water on the lungs)
Cardiac arrest
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Hypoaesthesia (reduced sense of touch or sensation)
Hypotension (abnormally low blood pressure)
Palpitations (feelings or sensations that your heart is pounding or racing)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pericardial effusion (fluid around the heart)

What are the common drug interactions of Zithromax and Definity, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Dyspnoea (difficult or laboured respiration)

30-39:

n/a

40-49:

Alanine aminotransferase increased

50-59:

Pulmonary oedema (fluid accumulation in the lungs)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Anaphylactic reaction (serious allergic reaction)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Hypoaesthesia (reduced sense of touch or sensation)
Hypotension (abnormally low blood pressure)
Muscle spasms (muscle contraction)

60+:

Dyspnoea (difficult or laboured respiration)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bradycardia (abnormally slow heart action)
Cardiac arrest
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chest pain
Cough
Dry mouth
Erythema (redness of the skin)
Flushing (the warm, red condition of human skin)

What are the existing conditions these people have? *

Pneumonia: 1 person, 5.26%
Pain: 1 person, 5.26%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 5.26%
Muscle Spasms (muscle contraction): 1 person, 5.26%
Hypertrophic Cardiomyopathy (a condition in which the heart muscle becomes abnormally thick): 1 person, 5.26%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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