Mirabegron and Valproate sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mirabegron (mirabegron) and Valproate sodium (valproate sodium). Common drug interactions include hepatitis fulminant among females and colitis among males.

The phase IV clinical study analyzes what interactions people have when they take Mirabegron and Valproate sodium. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Mirabegron?

Mirabegron has active ingredients of mirabegron. It is often used in urge incontinence. eHealthMe is studying from 5,414 Mirabegron users. Check the latest studies of Mirabegron.

What is Valproate sodium?

Valproate sodium has active ingredients of valproate sodium. It is often used in epilepsy. eHealthMe is studying from 24,044 Valproate sodium users. Check the latest studies of Valproate sodium.



On Jul, 10, 2026

19 people who take Mirabegron and Valproate sodium together, and have interactions are studied.

Mirabegron and Valproate sodium drug interactions.

What are the common drug interactions of Mirabegron and Valproate Sodium, by gender? *:

female:

  1. Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
  2. Inappropriate antidiuretic hormone secretion
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  5. Pneumonia
  6. Septic shock (shock due to blood infection)

male:

  1. Colitis (inflammation of colon)
  2. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  3. Thirst
  4. Vision blurred
  5. Abdominal pain lower
  6. Hyperkalaemia (damage to or disease of the kidney)
  7. Pain
  8. Rectal haemorrhage (bleeding from anus)
  9. Cellulitis (infection under the skin)
  10. Gastrointestinal disorder (functional problems of gastrointestinal tract)

What are the common drug interactions of Mirabegron and Valproate Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Colitis (inflammation of colon)
  2. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  3. Pain
  4. Pneumonia
  5. Rectal haemorrhage (bleeding from anus)
  6. Septic shock (shock due to blood infection)
  7. Hypokinesia (decreased bodily movement)
  8. Pyrexia (fever)
  9. Abdominal pain lower
  10. Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)

What are the existing conditions these people have? *

  1. Bipolar Disorder (mood disorder): 6 people, 31.58%
  2. Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 10.53%
  3. Micturition Urgency (urgency to pass the urine): 2 people, 10.53%
  4. Depression: 2 people, 10.53%
  5. Gastric Ulcer (stomach ulcer): 1 person, 5.26%
  6. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 5.26%
  7. Bladder Irritation: 1 person, 5.26%
  8. Cellulitis (infection under the skin): 1 person, 5.26%
  9. Constipation: 1 person, 5.26%
  10. Enlarged Prostate: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mirabegron and Valproate sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mirabegron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Valproate sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mirabegron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valproate sodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on mirabegron and valproate sodium (the active ingredients of Mirabegron and Valproate sodium, respectively), and Mirabegron and Valproate sodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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