Neupogen and Hypertensive crisis - a phase IV clinical study of FDA data

Summary:

Hypertensive crisis is reported as a side effect among people who take Neupogen (filgrastim), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Allopurinol, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Hypertensive crisis when taking Neupogen. It is created by eHealthMe based on reports of 23,793 people who have side effects when taking Neupogen from the FDA, and is updated regularly.

What is Neupogen?

Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.

What is Hypertensive crisis?

Hypertensive crisis is found to be associated with 789 drugs and 931 conditions by eHealthMe. Check the latest studies of Hypertensive crisis.

On Jul, 11, 2026

23,793 people reported to have side effects when taking Neupogen.
Among them, 16 people (0.07%) have Hypertensive crisis.

Could Neupogen cause Hypertensive crisis?

Among these 16 people:

How long have people been on Neupogen when they have Hypertensive crisis? *

What is the gender of people who have Hypertensive crisis when taking Neupogen? *

female: 50 %
male: 50 %

What is the age of people who have Hypertensive crisis when taking Neupogen? *

What are other drugs people take besides Neupogen? *

What are other side effects people have besides Hypertensive crisis? *

Acute Pulmonary Oedema (sudden deposit of fluid in the lung)): 7 people, 43.75%
Haematoma (collection of blood outside the blood vessels): 5 people, 31.25%
Febrile Neutropenia (fever with reduced white blood cells): 5 people, 31.25%
Thrombocytopenia (decrease of platelets in blood): 4 people, 25.00%
Leukaemia Plasmacytic (a progressive, malignant disease of the blood-forming organs): 3 people, 18.75%
Diarrhea: 3 people, 18.75%
Anaemia (lack of blood): 3 people, 18.75%
Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 3 people, 18.75%
White Blood Cell Count Decreased: 2 people, 12.50%
Arrhythmias (irregular heartbeat): 2 people, 12.50%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 8 people, 50.00%
Febrile Neutropenia (fever with reduced white blood cells): 7 people, 43.75%
Pleural Disorder: 7 people, 43.75%
Nausea (feeling of having an urge to vomit): 7 people, 43.75%
Bleeding Disorders: 7 people, 43.75%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 43.75%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 7 people, 43.75%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 4 people, 25.00%
Diarrhea: 4 people, 25.00%
Acute Pulmonary Oedema (sudden deposit of fluid in the lung)): 3 people, 18.75%

* Approximation only. Some reports may have incomplete information.

Do you take Neupogen and have Hypertensive crisis?

- Check whether Hypertensive crisis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Neupogen:

Neupogen (23,898 reports)

Browse all side effects of Neupogen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertensive crisis:

Hypertensive crisis (789 drugs)

Browse all the conditions that are associated with Hypertensive crisis:

Hypertensive crisis (931 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on filgrastim (the active ingredients of Neupogen) and Neupogen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.