Neupogen and Jaw disorder - a phase IV clinical study of FDA data

Summary:

Jaw disorder is reported as a side effect among people who take Neupogen (filgrastim), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Zometa, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Jaw disorder when taking Neupogen. It is created by eHealthMe based on reports of 23,793 people who have side effects when taking Neupogen from the FDA, and is updated regularly.

What is Neupogen?

Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.

What is Jaw disorder?

Jaw disorder (jaw disease) is found to be associated with 744 drugs and 1,054 conditions by eHealthMe. Check the latest studies of Jaw disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

23,793 people reported to have side effects when taking Neupogen.
Among them, 60 people (0.25%) have Jaw disorder.

Among these 60 people:

How long have people been on Neupogen when they have Jaw disorder? *

What is the gender of people who have Jaw disorder when taking Neupogen? *

female: 75 %
male: 25 %

What is the age of people who have Jaw disorder when taking Neupogen? *

What are other drugs people take besides Neupogen? *

Zometa: 56 people, 93.33%
Thalidomide: 36 people, 60.00%
Aredia: 35 people, 58.33%
Decadron: 26 people, 43.33%
Ativan: 23 people, 38.33%
Melphalan Hydrochloride: 19 people, 31.67%
Fosamax: 18 people, 30.00%
Rituxan: 16 people, 26.67%
Provera: 16 people, 26.67%
Premarin: 15 people, 25.00%

What are other side effects people have besides Jaw disorder? *

Bone Disorder: 49 people, 81.67%
Pain In Jaw: 37 people, 61.67%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 37 people, 61.67%
Fever: 32 people, 53.33%
Osteonecrosis Of Jaw (death of bone of jaw): 30 people, 50.00%
Bone Swelling: 29 people, 48.33%
Weakness: 29 people, 48.33%
Mastication Disorder (disease of chewing food): 27 people, 45.00%
Cellulitis (infection under the skin): 27 people, 45.00%
Weight Decreased: 26 people, 43.33%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 35 people, 58.33%
Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 16 people, 26.67%
Immunodeficiency Disorders: 16 people, 26.67%
Pain: 14 people, 23.33%
Fever: 4 people, 6.67%
Plasmacytoma (neoplasm of plasma cells (usually in bone marrow)): 4 people, 6.67%
Mucosal Inflammation (infection of mucous membrane): 4 people, 6.67%
Escherichia Bacteraemia (presence of bacteria escherichia coli in the blood): 3 people, 5.00%
Metastases To Bone (cancer spreads to bone): 3 people, 5.00%
Nausea (feeling of having an urge to vomit): 2 people, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Neupogen and have Jaw disorder?

- Check whether Jaw disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Neupogen:

Neupogen (23,898 reports)

Jaw disorder treatments and more:

Jaw disorder (9,029 reports)

Browse all side effects of Neupogen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Jaw disorder:

Jaw disorder (744 drugs)

Browse all the conditions that are associated with Jaw disorder:

Jaw disorder (1,054 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on filgrastim (the active ingredients of Neupogen) and Neupogen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.