Neupogen and Lactic acidosis - a phase IV clinical study of FDA data

Summary:

Lactic acidosis is reported as a side effect among people who take Neupogen (filgrastim), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Diflucan, and have Acute myeloid leukaemia.

The phase IV clinical study analyzes which people have Lactic acidosis when taking Neupogen. It is created by eHealthMe based on reports of 23,793 people who have side effects when taking Neupogen from the FDA, and is updated regularly.

What is Neupogen?

Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.

What is Lactic acidosis?

Lactic acidosis (low ph in body tissues) is found to be associated with 994 drugs and 1,277 conditions by eHealthMe. Check the latest studies of Lactic acidosis.

On Jul, 19, 2026

23,793 people reported to have side effects when taking Neupogen.
Among them, 23 people (0.1%) have Lactic acidosis.

Among these 23 people:

How long have people been on Neupogen when they have Lactic acidosis? *

What is the gender of people who have Lactic acidosis when taking Neupogen? *

female: 68.18 %
male: 31.82 %

What is the age of people who have Lactic acidosis when taking Neupogen? *

What are other drugs people take besides Neupogen? *

What are other side effects people have besides Lactic acidosis? *

Acute Kidney Failure: 10 people, 43.48%
Multi-Organ Failure (multisystem organ failure): 8 people, 34.78%
Fever: 6 people, 26.09%
Nausea And Vomiting: 6 people, 26.09%
Hepatomegaly (abnormal enlargement of the liver): 5 people, 21.74%
Nausea (feeling of having an urge to vomit): 5 people, 21.74%
Fatigue (feeling of tiredness): 5 people, 21.74%
Diarrhea: 5 people, 21.74%
Blood Electrolytes Abnormal: 4 people, 17.39%
Back Pain: 4 people, 17.39%

What are the existing conditions these people have? *

Aplastic Anemia: 3 people, 13.04%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 13.04%
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 2 people, 8.70%
Hodgkin's Lymphoma (cancer originating from white blood cells): 2 people, 8.70%
Hiv Infection: 2 people, 8.70%
Type 2 Diabetes: 1 person, 4.35%
Septic Shock (shock due to blood infection): 1 person, 4.35%
Nausea (feeling of having an urge to vomit): 1 person, 4.35%
Multiple Myeloma (cancer of the plasma cells): 1 person, 4.35%
Leukopenia (less number of white blood cells in blood): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Neupogen and have Lactic acidosis?

- Check whether Lactic acidosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Neupogen:

Neupogen (23,898 reports)

Lactic acidosis treatments and more:

Lactic acidosis (34,314 reports)

Browse all side effects of Neupogen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lactic acidosis:

Lactic acidosis (994 drugs)

Browse all the conditions that are associated with Lactic acidosis:

Lactic acidosis (1,277 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on filgrastim (the active ingredients of Neupogen) and Neupogen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.