Neupogen and Osteosclerosis - a phase IV clinical study of FDA data

Summary:

Osteosclerosis is reported as a side effect among people who take Neupogen (filgrastim), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Zometa, and have Breast cancer.

The phase IV clinical study analyzes which people have Osteosclerosis when taking Neupogen. It is created by eHealthMe based on reports of 23,793 people who have side effects when taking Neupogen from the FDA, and is updated regularly.

What is Neupogen?

Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.

What is Osteosclerosis?

Osteosclerosis (an elevation in bone density) is found to be associated with 636 drugs and 399 conditions by eHealthMe. Check the latest studies of Osteosclerosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 28, 2026

23,793 people reported to have side effects when taking Neupogen.
Among them, 75 people (0.32%) have Osteosclerosis.

Could Neupogen cause Osteosclerosis?

Among these 75 people:

How long have people been on Neupogen when they have Osteosclerosis? *

  • < 1 month: 33.33 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 66.67 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Osteosclerosis when taking Neupogen? *

  • female: 72.31 %
  • male: 27.69 %

What is the age of people who have Osteosclerosis when taking Neupogen? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 3.45 %
  • 20-29: 1.72 %
  • 30-39: 0.0 %
  • 40-49: 22.41 %
  • 50-59: 53.45 %
  • 60+: 18.97 %

What are other drugs people take besides Neupogen? *

  1. Zometa: 75 people, 100.00%
  2. Aredia: 51 people, 68.00%
  3. Taxotere: 40 people, 53.33%
  4. Compazine: 36 people, 48.00%
  5. Ambien: 31 people, 41.33%
  6. Methotrexate: 30 people, 40.00%
  7. Ativan: 30 people, 40.00%
  8. Neurontin: 29 people, 38.67%
  9. Adriamycin Pfs: 28 people, 37.33%
  10. Taxol: 26 people, 34.67%

What are other side effects people have besides Osteosclerosis? *

  1. Pain In Jaw: 65 people, 86.67%
  2. Bone Disorder: 64 people, 85.33%
  3. Osteonecrosis Of Jaw (death of bone of jaw): 60 people, 80.00%
  4. Injury: 56 people, 74.67%
  5. Anaemia (lack of blood): 52 people, 69.33%
  6. Stress And Anxiety: 47 people, 62.67%
  7. Impaired Healing: 45 people, 60.00%
  8. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 45 people, 60.00%
  9. Intervertebral Disc Protrusion (spinal disc protrusion): 45 people, 60.00%
  10. Joint Pain: 44 people, 58.67%

What are the existing conditions these people have? *

  1. Breast Cancer: 32 people, 42.67%
  2. Breast Cancer Metastatic: 30 people, 40.00%
  3. Metastases To Bone (cancer spreads to bone): 23 people, 30.67%
  4. Migraine (headache): 22 people, 29.33%
  5. Discomfort: 22 people, 29.33%
  6. Granulocyte Count Decreased: 22 people, 29.33%
  7. Hot Flush (sudden feelings of heat): 22 people, 29.33%
  8. Ovarian Cancer (cancer of ovary): 22 people, 29.33%
  9. Neoplasm Malignant (cancer tumour): 22 people, 29.33%
  10. Multiple Myeloma (cancer of the plasma cells): 14 people, 18.67%

* Approximation only. Some reports may have incomplete information.

Do you take Neupogen and have Osteosclerosis?

- Check whether Osteosclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Neupogen:

Osteosclerosis treatments and more:

How severe was Osteosclerosis and when was it recovered:

Expand to all the drugs that have ingredients of filgrastim:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Neupogen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteosclerosis:

Browse all the conditions that are associated with Osteosclerosis:


How the study uses the data?

The study uses data from the FDA. It is based on filgrastim (the active ingredients of Neupogen) and Neupogen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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