Neurontin and Brain damage - a phase IV clinical study of FDA data

Summary:

Brain damage is reported as a side effect among people who take Neurontin (gabapentin), especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years also take Clonazepam, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Brain damage when taking Neurontin. It is created by eHealthMe based on reports of 103,969 people who have side effects when taking Neurontin from the FDA, and is updated regularly.

What is Neurontin?

Neurontin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 107,468 Neurontin users. Check the latest studies of Neurontin.

What is Brain damage?

Brain damage is found to be associated with 84 drugs and 281 conditions by eHealthMe. Check the latest studies of Brain damage.

On Aug, 07, 2026

103,969 people reported to have side effects when taking Neurontin.
Among them, 46 people (0.04%) have Brain damage.

Among these 46 people:

How long have people been on Neurontin when they have Brain damage? *

What is the gender of people who have Brain damage when taking Neurontin? *

female: 73.91 %
male: 26.09 %

What is the age of people who have Brain damage when taking Neurontin? *

What are other drugs people take besides Neurontin? *

Celebrex: 12 people, 26.09%
Clonazepam: 12 people, 26.09%
Metoprolol Succinate: 11 people, 23.91%
Lamotrigine: 11 people, 23.91%
Lansoprazole: 11 people, 23.91%
Diltiazem Hydrochloride: 11 people, 23.91%
Lithium Carbonate: 11 people, 23.91%
Levothyroxine Sodium: 11 people, 23.91%
Liothyronine Sodium: 10 people, 21.74%
Metoprolol Tartrate: 8 people, 17.39%

What are other side effects people have besides Brain damage? *

Depression: 18 people, 39.13%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 13 people, 28.26%
Speech Disorder: 12 people, 26.09%
Road Traffic Accident: 12 people, 26.09%
Swollen Tongue (swelling of tongue): 10 people, 21.74%
Insomnia (sleeplessness): 10 people, 21.74%
Loss Of Consciousness: 10 people, 21.74%
Drug Hypersensitivity: 9 people, 19.57%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 9 people, 19.57%
Fainting (loss of consciousness and postural tone): 8 people, 17.39%

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 13 people, 28.26%
Ill-Defined Disorder: 9 people, 19.57%
Neuropathic Pain (pain due to nerve inflammation and damage): 5 people, 10.87%
Headache (pain in head): 5 people, 10.87%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 8.70%
Birth Control: 3 people, 6.52%
Abdominal Pain: 3 people, 6.52%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 4.35%
Migraine (headache): 2 people, 4.35%
Sinusitis (inflammation of sinus): 1 person, 2.17%

* Approximation only. Some reports may have incomplete information.

Do you take Neurontin and have Brain damage?

- Check whether Brain damage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Neurontin:

Neurontin (107,468 reports)

Brain damage treatments and more:

Brain damage (1,024 reports)

Browse all side effects of Neurontin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Brain damage:

Brain damage (84 drugs)

Browse all the conditions that are associated with Brain damage:

Brain damage (281 conditions)

Related publications that referenced our studies

de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on gabapentin (the active ingredients of Neurontin) and Neurontin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.