Neurontin and Clonus - a phase IV clinical study of FDA data
Summary:
Clonus is reported as a side effect among people who take Neurontin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Celexa, and have Muscle spasms.
The phase IV clinical study analyzes which people have Clonus when taking Neurontin. It is created by eHealthMe based on reports of 103,969 people who have side effects when taking Neurontin from the FDA, and is updated regularly.
What is Neurontin?
Neurontin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 107,468 Neurontin users. Check the latest studies of Neurontin.
What is Clonus?
Clonus (series of involuntary, rhythmic, muscular contractions and relaxations) is found to be associated with 290 drugs and 561 conditions by eHealthMe. Check the latest studies of Clonus.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
103,969 people reported to have side effects when taking Neurontin.
Among them, 22 people (0.02%) have Clonus.

Among these 22 people:
How long have people been on Neurontin when they have Clonus? *
- < 1 month: 50 %
- 1 - 6 months: 50 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Clonus when taking Neurontin? *
- female: 65 %
- male: 35 %
What is the age of people who have Clonus when taking Neurontin? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 10 %
- 40-49: 30 %
- 50-59: 30 %
- 60+: 30 %
What are other drugs people take besides Neurontin? *
- Cymbalta: 7 people, 31.82%
- Celexa: 7 people, 31.82%
- Zoloft: 5 people, 22.73%
- Celebrex: 4 people, 18.18%
- Fentanyl: 4 people, 18.18%
- Morphine: 4 people, 18.18%
- Baclofen: 4 people, 18.18%
- Tysabri: 3 people, 13.64%
- Ditropan: 3 people, 13.64%
- Folic Acid: 3 people, 13.64%
What are other side effects people have besides Clonus? *
- Fall: 7 people, 31.82%
- Stress And Anxiety: 6 people, 27.27%
- Movement - Uncoordinated: 6 people, 27.27%
- Pneumonia: 5 people, 22.73%
- Tremor (trembling or shaking movements in one or more parts of your body): 5 people, 22.73%
- Headache (pain in head): 5 people, 22.73%
- Weakness: 5 people, 22.73%
- Muscle Aches (muscle pain): 4 people, 18.18%
- Constipation: 4 people, 18.18%
- Drug Toxicity: 4 people, 18.18%
What are the existing conditions these people have? *
- Muscle Spasms (muscle contraction): 5 people, 22.73%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 18.18%
- Laxative Supportive Care: 2 people, 9.09%
- Hepatitis C: 2 people, 9.09%
- Constipation: 2 people, 9.09%
- Pain In Extremity: 2 people, 9.09%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 9.09%
- Drowsiness: 2 people, 9.09%
- Drug Dependence: 1 person, 4.55%
- Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 1 person, 4.55%
* Approximation only. Some reports may have incomplete information.
Do you take Neurontin and have Clonus?
- Check whether Clonus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Neurontin:
- Neurontin (107,468 reports)
Clonus treatments and more:
- Clonus (3,236 reports)
How severe was Clonus and when was it recovered:
Expand to all the drugs that have ingredients of gabapentin:
- Clonus and drugs with ingredients of gabapentin (159 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Neurontin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Clonus:
- Clonus (290 drugs)
Browse all the conditions that are associated with Clonus:
- Clonus (561 conditions)
Related publications that referenced our studies
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on gabapentin (the active ingredients of Neurontin) and Neurontin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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