Neurontin and Macule - a phase IV clinical study of FDA data

Summary:

Macule is reported as a side effect among people who take Neurontin (gabapentin), especially for people who are female, 40-49 old, also take Ativan, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Macule when taking Neurontin. It is created by eHealthMe based on reports of 103,969 people who have side effects when taking Neurontin from the FDA, and is updated regularly.

What is Neurontin?

Neurontin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 107,468 Neurontin users. Check the latest studies of Neurontin.

What is Macule?

Macule (a discoloured spot on the skin) is found to be associated with 287 drugs and 710 conditions by eHealthMe. Check the latest studies of Macule.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

103,969 people reported to have side effects when taking Neurontin.
Among them, 19 people (0.02%) have Macule.

Among these 19 people:

What is the gender of people who have Macule when taking Neurontin? *

female: 94.12 %
male: 5.88 %

What is the age of people who have Macule when taking Neurontin? *

What are other drugs people take besides Neurontin? *

What are other side effects people have besides Macule? *

Rashes (redness): 14 people, 73.68%
Emotional Distress: 13 people, 68.42%
Neuropathy Peripheral (surface nerve damage): 13 people, 68.42%
Osteomyelitis (infection of bone): 13 people, 68.42%
Osteonecrosis Of Jaw (death of bone of jaw): 13 people, 68.42%
Bone Lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 13 people, 68.42%
Muscle Spasms (muscle contraction): 13 people, 68.42%
Pain In Jaw: 13 people, 68.42%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 13 people, 68.42%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 13 people, 68.42%

What are the existing conditions these people have? *

Stress And Anxiety: 11 people, 57.89%
Upper Respiratory Tract Infection: 2 people, 10.53%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 10.53%
Muscle Spasms (muscle contraction): 2 people, 10.53%
Multiple Myeloma (cancer of the plasma cells): 2 people, 10.53%
Bone Lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 2 people, 10.53%
Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 1 person, 5.26%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 5.26%
Partial Seizures (seizures which affect only a part of the brain at onset): 1 person, 5.26%
Osteoporosis (bones weak and more likely to break): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Neurontin and have Macule?

- Check whether Macule is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Neurontin:

Neurontin (107,468 reports)

Macule treatments and more:

Macule (3,263 reports)

Browse all side effects of Neurontin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Macule:

Macule (287 drugs)

Browse all the conditions that are associated with Macule:

Macule (710 conditions)

Related publications that referenced our studies

de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on gabapentin (the active ingredients of Neurontin) and Neurontin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.