Nexavar and Flank pain - a phase IV clinical study of FDA data

Summary:

Flank pain is reported as a side effect among people who take Nexavar (sorafenib tosylate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Stivarga, and have Colon cancer.

The phase IV clinical study analyzes which people have Flank pain when taking Nexavar. It is created by eHealthMe based on reports of 23,142 people who have side effects when taking Nexavar from the FDA, and is updated regularly.

What is Nexavar?

Nexavar has active ingredients of sorafenib tosylate. It is often used in hepatocellular carcinoma. eHealthMe is studying from 23,250 Nexavar users. Check the latest studies of Nexavar.

What is Flank pain?

Flank pain (a distressing sensation experienced around the lower back and the upper abdomen) is found to be associated with 1,133 drugs and 1,476 conditions by eHealthMe. Check the latest studies of Flank pain.



On Jul, 13, 2026

23,142 people reported to have side effects when taking Nexavar.
Among them, 31 people (0.13%) have Flank pain.

Could Nexavar cause Flank pain?

Among these 31 people:

How long have people been on Nexavar when they have Flank pain? *

  • < 1 month: 90 %
  • 1 - 6 months: 10 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Flank pain when taking Nexavar? *

  • female: 32.26 %
  • male: 67.74 %

What is the age of people who have Flank pain when taking Nexavar? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 10.71 %
  • 60+: 89.29 %

What are other drugs people take besides Nexavar? *

  1. Benadryl: 4 people, 12.90%
  2. Stivarga: 4 people, 12.90%
  3. Zantac: 3 people, 9.68%
  4. Oxycontin: 3 people, 9.68%
  5. Ativan: 2 people, 6.45%
  6. Tagamet: 2 people, 6.45%
  7. Clobetasol Propionate: 2 people, 6.45%
  8. Centrum Silver: 2 people, 6.45%
  9. Diovan: 2 people, 6.45%
  10. Vicodin: 2 people, 6.45%

What are other side effects people have besides Flank pain? *

  1. Rashes (redness): 14 people, 45.16%
  2. Palmar-Plantar Erythrodysaesthesia Syndrome (hand-foot syndrome): 14 people, 45.16%
  3. Weakness: 11 people, 35.48%
  4. Diarrhea: 11 people, 35.48%
  5. Nausea (feeling of having an urge to vomit): 10 people, 32.26%
  6. Fatigue (feeling of tiredness): 10 people, 32.26%
  7. Abdominal Pain: 9 people, 29.03%
  8. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 9 people, 29.03%
  9. Dyspnea (difficult or laboured breathing): 9 people, 29.03%
  10. High Blood Pressure: 9 people, 29.03%

What are the existing conditions these people have? *

  1. Pain: 3 people, 9.68%
  2. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 3 people, 9.68%
  3. Colon Cancer: 3 people, 9.68%
  4. Insomnia (sleeplessness): 2 people, 6.45%
  5. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 6.45%
  6. Urinary Tract Infection: 1 person, 3.23%
  7. Soft Tissue Neoplasm (tumour of soft tissue): 1 person, 3.23%
  8. Renal Cell Carcinoma Stage Unspecified (kidney cancer in unknown stage): 1 person, 3.23%
  9. Renal Cell Carcinoma Stage Iv (stage iv renal cell cancer have cancer that has spread to other organs, such as the lungs, liver, bones, or brain, and may have spread to lymph nodes): 1 person, 3.23%
  10. Malignant Urinary Tract Neoplasm (cancer tumour of urinary tract organs): 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Nexavar and have Flank pain?

- Check whether Flank pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nexavar:

Flank pain treatments and more:

How severe was Flank pain and when was it recovered:

Expand to all the drugs that have ingredients of sorafenib tosylate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nexavar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Flank pain:

Browse all the conditions that are associated with Flank pain:


How the study uses the data?

The study uses data from the FDA. It is based on sorafenib tosylate (the active ingredients of Nexavar) and Nexavar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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