Nexavar and Osteoarthritis - a phase IV clinical study of FDA data

Summary:

Osteoarthritis is reported as a side effect among people who take Nexavar (sorafenib tosylate), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Osteoarthritis when taking Nexavar. It is created by eHealthMe based on reports of 23,142 people who have side effects when taking Nexavar from the FDA, and is updated regularly.

What is Nexavar?

Nexavar has active ingredients of sorafenib tosylate. It is often used in hepatocellular carcinoma. eHealthMe is studying from 23,250 Nexavar users. Check the latest studies of Nexavar.

What is Osteoarthritis?

Osteoarthritis (a joint disease caused by cartilage loss in a joint) is found to be associated with 1,877 drugs and 2,645 conditions by eHealthMe. Check the latest studies of Osteoarthritis.

On Jul, 21, 2026

23,142 people reported to have side effects when taking Nexavar.
Among them, 47 people (0.2%) have Osteoarthritis.

Among these 47 people:

How long have people been on Nexavar when they have Osteoarthritis? *

What is the gender of people who have Osteoarthritis when taking Nexavar? *

female: 40.43 %
male: 59.57 %

What is the age of people who have Osteoarthritis when taking Nexavar? *

What are other drugs people take besides Nexavar? *

What are other side effects people have besides Osteoarthritis? *

Stress And Anxiety: 36 people, 76.60%
Pain: 35 people, 74.47%
Osteonecrosis Of Jaw (death of bone of jaw): 35 people, 74.47%
Injury: 33 people, 70.21%
Pneumonia: 29 people, 61.70%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 27 people, 57.45%
Haematuria (presence of blood in urine): 26 people, 55.32%
Dyspnea (difficult or laboured breathing): 26 people, 55.32%
Abdominal Pain: 25 people, 53.19%
Chest Pain: 25 people, 53.19%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 11 people, 23.40%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 2 people, 4.26%
Renal Cell Carcinoma Stage Iv (stage iv renal cell cancer have cancer that has spread to other organs, such as the lungs, liver, bones, or brain, and may have spread to lymph nodes): 2 people, 4.26%
Pain: 2 people, 4.26%
Hepatic Neoplasm Malignant (liver cancer): 2 people, 4.26%
Cardiac Disorder: 1 person, 2.13%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 2.13%
Desmoid Tumor: 1 person, 2.13%
Diabetes: 1 person, 2.13%
Eye Disorder: 1 person, 2.13%

* Approximation only. Some reports may have incomplete information.

Do you take Nexavar and have Osteoarthritis?

- Check whether Osteoarthritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nexavar:

Nexavar (23,250 reports)

Osteoarthritis treatments and more:

Osteoarthritis (95,654 reports)

Browse all side effects of Nexavar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteoarthritis:

Osteoarthritis (1,877 drugs)

Browse all the conditions that are associated with Osteoarthritis:

Osteoarthritis (2,645 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sorafenib tosylate (the active ingredients of Nexavar) and Nexavar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.