Nexium and Right ventricular dysfunction - a phase IV clinical study of FDA data

Summary:

Right ventricular dysfunction is reported as a side effect among people who take Nexium (esomeprazole magnesium), especially for people who are female, 60+ old, also take Adcirca, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Right ventricular dysfunction when taking Nexium. It is created by eHealthMe based on reports of 240,870 people who have side effects when taking Nexium from the FDA, and is updated regularly.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,678 Nexium users. Check the latest studies of Nexium.

What is Right ventricular dysfunction?

Right ventricular dysfunction is found to be associated with 182 drugs and 250 conditions by eHealthMe. Check the latest studies of Right ventricular dysfunction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

240,870 people reported to have side effects when taking Nexium.
Among them, 14 people (0.01%) have Right ventricular dysfunction.

Could Nexium cause Right ventricular dysfunction?

Among these 14 people:

What is the gender of people who have Right ventricular dysfunction when taking Nexium? *

female: 54.55 %
male: 45.45 %

What is the age of people who have Right ventricular dysfunction when taking Nexium? *

What are other drugs people take besides Nexium? *

What are other side effects people have besides Right ventricular dysfunction? *

Dyspnea (difficult or laboured breathing): 9 people, 64.29%
Cardiogenic Shock (inadequate circulation of blood): 5 people, 35.71%
Oedema Peripheral (superficial swelling): 5 people, 35.71%
Arrhythmias (irregular heartbeat): 4 people, 28.57%
Fatigue (feeling of tiredness): 4 people, 28.57%
Nausea (feeling of having an urge to vomit): 4 people, 28.57%
Death: 4 people, 28.57%
Acute Kidney Failure: 3 people, 21.43%
Left Ventricular Dysfunction: 3 people, 21.43%
Head Injury: 3 people, 21.43%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 9 people, 64.29%
Upper-Airway Cough Syndrome: 2 people, 14.29%
Stress And Anxiety: 2 people, 14.29%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 14.29%
Oedema Peripheral (superficial swelling): 2 people, 14.29%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 2 people, 14.29%
Cough: 2 people, 14.29%
Indigestion: 1 person, 7.14%
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 1 person, 7.14%
Drug Resistance (reduction in effectiveness of a drug): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Nexium and have Right ventricular dysfunction?

- Check whether Right ventricular dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nexium:

Nexium (245,678 reports)

Browse all side effects of Nexium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Right ventricular dysfunction:

Right ventricular dysfunction (182 drugs)

Browse all the conditions that are associated with Right ventricular dysfunction:

Right ventricular dysfunction (250 conditions)

Related publications that referenced our studies

Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on esomeprazole magnesium (the active ingredients of Nexium) and Nexium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.