Nexium and Sialoadenitis - a phase IV clinical study of FDA data
Summary:
Sialoadenitis is reported as a side effect among people who take Nexium (esomeprazole magnesium), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Fosamax, and have Osteoporosis.
The phase IV clinical study analyzes which people have Sialoadenitis when taking Nexium. It is created by eHealthMe based on reports of 240,870 people who have side effects when taking Nexium from the FDA, and is updated regularly.
What is Nexium?
Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,677 Nexium users. Check the latest studies of Nexium.
What is Sialoadenitis?
Sialoadenitis (inflammation of a salivary gland) is found to be associated with 342 drugs and 326 conditions by eHealthMe. Check the latest studies of Sialoadenitis.
240,870 people reported to have side effects when taking Nexium.
Among them, 49 people (0.02%) have Sialoadenitis.

Among these 49 people:
How long have people been on Nexium when they have Sialoadenitis? *
- < 1 month: 12.5 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 50.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 37.5 %
- 10+ years: 0.0 %
What is the gender of people who have Sialoadenitis when taking Nexium? *
- female: 61.7 %
- male: 38.3 %
What is the age of people who have Sialoadenitis when taking Nexium? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 13.64 %
- 40-49: 9.09 %
- 50-59: 13.64 %
- 60+: 63.64 %
What are other drugs people take besides Nexium? *
- Oxycontin: 12 people, 24.49%
- Fosamax: 12 people, 24.49%
- Xanax: 9 people, 18.37%
- Zometa: 9 people, 18.37%
- Prilosec: 9 people, 18.37%
- Reglan: 8 people, 16.33%
- Metoclopramide: 8 people, 16.33%
- Neurontin: 8 people, 16.33%
- Zantac: 8 people, 16.33%
- Zofran: 8 people, 16.33%
What are other side effects people have besides Sialoadenitis? *
- Back Pain: 19 people, 38.78%
- Chest Pain: 17 people, 34.69%
- Anaemia (lack of blood): 16 people, 32.65%
- Dyspnea (difficult or laboured breathing): 15 people, 30.61%
- Fall: 14 people, 28.57%
- Impaired Healing: 13 people, 26.53%
- Mouth Ulcers: 13 people, 26.53%
- Joint Pain: 13 people, 26.53%
- Dehydration (dryness resulting from the removal of water): 13 people, 26.53%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 12 people, 24.49%
What are the existing conditions these people have? *
- Osteoporosis (bones weak and more likely to break): 14 people, 28.57%
- Osteopenia (a condition where bone mineral density is lower than normal): 10 people, 20.41%
- Pain: 8 people, 16.33%
- High Blood Pressure: 7 people, 14.29%
- Breast Cancer: 7 people, 14.29%
- Metastases To Bone (cancer spreads to bone): 7 people, 14.29%
- Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 7 people, 14.29%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 12.24%
- Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 6 people, 12.24%
- Meniere's Disease (a disorder of the inner ear that can affect hearing and balance to a varying degree): 5 people, 10.20%
* Approximation only. Some reports may have incomplete information.
Do you take Nexium and have Sialoadenitis?
- Check whether Sialoadenitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Nexium:
- Nexium (245,677 reports)
Sialoadenitis treatments and more:
- Sialoadenitis (1,917 reports)
How severe was Sialoadenitis and when was it recovered:
Expand to all the drugs that have ingredients of esomeprazole magnesium:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nexium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Sialoadenitis:
- Sialoadenitis (342 drugs)
Browse all the conditions that are associated with Sialoadenitis:
- Sialoadenitis (326 conditions)
Related publications that referenced our studies
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on esomeprazole magnesium (the active ingredients of Nexium) and Nexium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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