Nexium and Wound dehiscence - a phase IV clinical study of FDA data

Summary:

Wound dehiscence is reported as a side effect among people who take Nexium (esomeprazole magnesium), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Zometa, and have High blood pressure.

The phase IV clinical study analyzes which people have Wound dehiscence when taking Nexium. It is created by eHealthMe based on reports of 240,870 people who have side effects when taking Nexium from the FDA, and is updated regularly.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,677 Nexium users. Check the latest studies of Nexium.

What is Wound dehiscence?

Wound dehiscence (a surgical incision reopens either internally or externally) is found to be associated with 658 drugs and 673 conditions by eHealthMe. Check the latest studies of Wound dehiscence.



On Jul, 13, 2026

240,870 people reported to have side effects when taking Nexium.
Among them, 99 people (0.04%) have Wound dehiscence.

Could Nexium cause Wound dehiscence?

Among these 99 people:

How long have people been on Nexium when they have Wound dehiscence? *

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 50 %

What is the gender of people who have Wound dehiscence when taking Nexium? *

  • female: 68.04 %
  • male: 31.96 %

What is the age of people who have Wound dehiscence when taking Nexium? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 1.12 %
  • 30-39: 14.61 %
  • 40-49: 12.36 %
  • 50-59: 38.2 %
  • 60+: 33.71 %

What are other drugs people take besides Nexium? *

  1. Zometa: 45 people, 45.45%
  2. Percocet: 40 people, 40.40%
  3. Lunesta: 32 people, 32.32%
  4. Neurontin: 32 people, 32.32%
  5. Ambien: 31 people, 31.31%
  6. Effexor: 29 people, 29.29%
  7. Vioxx: 28 people, 28.28%
  8. Celebrex: 27 people, 27.27%
  9. Oxycontin: 26 people, 26.26%
  10. Aredia: 25 people, 25.25%

What are other side effects people have besides Wound dehiscence? *

  1. Stress And Anxiety: 43 people, 43.43%
  2. Impaired Healing: 39 people, 39.39%
  3. Osteonecrosis Of Jaw (death of bone of jaw): 36 people, 36.36%
  4. Bone Disorder: 34 people, 34.34%
  5. Dyspnea (difficult or laboured breathing): 34 people, 34.34%
  6. Pain In Jaw: 33 people, 33.33%
  7. Weakness: 33 people, 33.33%
  8. Pain: 32 people, 32.32%
  9. Bone Lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 32 people, 32.32%
  10. Fall: 31 people, 31.31%

What are the existing conditions these people have? *

  1. High Blood Pressure: 34 people, 34.34%
  2. Metastases To Bone (cancer spreads to bone): 23 people, 23.23%
  3. Multiple Myeloma (cancer of the plasma cells): 22 people, 22.22%
  4. Depression: 13 people, 13.13%
  5. Pain: 11 people, 11.11%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 11 people, 11.11%
  7. Fatigue (feeling of tiredness): 10 people, 10.10%
  8. Hypercalcaemia (elevated calcium (ca+) level in the blood): 9 people, 9.09%
  9. Nausea (feeling of having an urge to vomit): 9 people, 9.09%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 9 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Nexium and have Wound dehiscence?

- Check whether Wound dehiscence is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nexium:

Wound dehiscence treatments and more:

How severe was Wound dehiscence and when was it recovered:

Expand to all the drugs that have ingredients of esomeprazole magnesium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nexium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Wound dehiscence:

Browse all the conditions that are associated with Wound dehiscence:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on esomeprazole magnesium (the active ingredients of Nexium) and Nexium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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