Nexplanon and Panic attacks - a phase IV clinical study of FDA data

Summary:

Panic attacks is reported as a side effect among people who take Nexplanon (etonogestrel), especially for people who are female, 20-29 old, have been taking the drug for 1 - 6 months also take Xanax, and have Cataplexy.

The phase IV clinical study analyzes which people have Panic attacks when taking Nexplanon. It is created by eHealthMe based on reports of 45,676 people who have side effects when taking Nexplanon from the FDA, and is updated regularly.

What is Nexplanon?

Nexplanon has active ingredients of etonogestrel. It is often used in birth control. eHealthMe is studying from 46,431 Nexplanon users. Check the latest studies of Nexplanon.

What is Panic attacks?

Panic attacks is found to be associated with 2,586 drugs and 2,067 conditions by eHealthMe. Check the latest studies of Panic attacks.



On Dec, 05, 2025

45,676 people reported to have side effects when taking Nexplanon.
Among them, 88 people (0.19%) have Panic attacks.

Could Nexplanon cause Panic attacks?

Among these 88 people:

How long have people been on Nexplanon when they have Panic attacks? *

  • < 1 month: 11.76 %
  • 1 - 6 months: 41.18 %
  • 6 - 12 months: 20.59 %
  • 1 - 2 years: 8.82 %
  • 2 - 5 years: 14.71 %
  • 5 - 10 years: 2.94 %
  • 10+ years: 0.0 %

What is the gender of people who have Panic attacks when taking Nexplanon? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Panic attacks when taking Nexplanon? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 18.92 %
  • 20-29: 51.35 %
  • 30-39: 24.32 %
  • 40-49: 4.05 %
  • 50-59: 1.35 %
  • 60+: 0.0 %

What are other drugs people take besides Nexplanon? *

  1. Xanax: 5 people, 5.68%
  2. Naproxen: 4 people, 4.55%
  3. Sertraline: 3 people, 3.41%
  4. Zoloft: 3 people, 3.41%
  5. Wellbutrin Sr: 2 people, 2.27%
  6. Azelastine: 2 people, 2.27%
  7. Xywav: 2 people, 2.27%
  8. Lexapro: 2 people, 2.27%
  9. Flonase Allergy Relief: 2 people, 2.27%
  10. Fluoxetine Hydrochloride: 2 people, 2.27%

What are other side effects people have besides Panic attacks? *

  1. Stress And Anxiety: 49 people, 55.68%
  2. Depression: 28 people, 31.82%
  3. Mood Swings (an extreme or rapid change in mood): 19 people, 21.59%
  4. Nausea (feeling of having an urge to vomit): 18 people, 20.45%
  5. Headache (pain in head): 18 people, 20.45%
  6. Suicidal Ideation: 17 people, 19.32%
  7. Dyspnea (difficult or laboured breathing): 14 people, 15.91%
  8. Weight Increased: 14 people, 15.91%
  9. Pain: 13 people, 14.77%
  10. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 11 people, 12.50%

What are the existing conditions these people have? *

  1. Stress And Anxiety: 3 people, 3.41%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 3.41%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 3.41%
  4. Drowsiness: 2 people, 2.27%
  5. Heavy Or Prolong Menstrual Bleeding: 1 person, 1.14%
  6. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 1.14%
  7. Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 1 person, 1.14%
  8. Dysmenorrhea (painful menstruation): 1 person, 1.14%
  9. Headache (pain in head): 1 person, 1.14%
  10. Hidradenitis (chronic disease of a type of sweat gland): 1 person, 1.14%

* Approximation only. Some reports may have incomplete information.

Do you take Nexplanon and have Panic attacks?

- Check whether Panic attacks is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nexplanon:

Panic attacks treatments and more:

How severe was Panic attacks and when was it recovered:

Expand to all the drugs that have ingredients of etonogestrel:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nexplanon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Panic attacks:

Browse all the conditions that are associated with Panic attacks:

Drugs similar to Nexplanon and Panic attacks :


How the study uses the data?

The study uses data from the FDA. It is based on etonogestrel (the active ingredients of Nexplanon) and Nexplanon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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