Niacin and Impaired work ability - a phase IV clinical study of FDA data

Summary:

Impaired work ability is reported as a side effect among people who take Niacin (niacin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Aspirin, and have Hypersensitivity.

The phase IV clinical study analyzes which people have Impaired work ability when taking Niacin. It is created by eHealthMe based on reports of 7,974 people who have side effects when taking Niacin from the FDA, and is updated regularly.

What is Niacin?

Niacin has active ingredients of niacin. It is often used in high blood cholesterol. eHealthMe is studying from 9,009 Niacin users. Check the latest studies of Niacin.

What is Impaired work ability?

Impaired work ability is found to be associated with 1,013 drugs and 1,139 conditions by eHealthMe. Check the latest studies of Impaired work ability.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

7,974 people reported to have side effects when taking Niacin.
Among them, 14 people (0.18%) have Impaired work ability.

Could Niacin cause Impaired work ability?

Among these 14 people:

How long have people been on Niacin when they have Impaired work ability? *

What is the gender of people who have Impaired work ability when taking Niacin? *

female: 35.71 %
male: 64.29 %

What is the age of people who have Impaired work ability when taking Niacin? *

What are other drugs people take besides Niacin? *

What are other side effects people have besides Impaired work ability? *

Pain: 4 people, 28.57%
Dyspnea (difficult or laboured breathing): 4 people, 28.57%
Drowsiness: 4 people, 28.57%
Diarrhea: 4 people, 28.57%
Gait Disturbance: 3 people, 21.43%
Nausea (feeling of having an urge to vomit): 3 people, 21.43%
Dizziness: 3 people, 21.43%
Depression: 3 people, 21.43%
Fatigue (feeling of tiredness): 3 people, 21.43%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 21.43%

What are the existing conditions these people have? *

Migraine (headache): 3 people, 21.43%
Hypersensitivity: 3 people, 21.43%
Abdominal Pain: 2 people, 14.29%
Dry Skin: 2 people, 14.29%
Pain: 2 people, 14.29%
Back Pain: 2 people, 14.29%
Bipolar Disorder (mood disorder): 2 people, 14.29%
Breakthrough Pain: 2 people, 14.29%
Depression: 2 people, 14.29%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Niacin and have Impaired work ability?

- Check whether Impaired work ability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Niacin:

Niacin (9,009 reports)

Browse all side effects of Niacin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Impaired work ability:

Impaired work ability (1,013 drugs)

Browse all the conditions that are associated with Impaired work ability:

Impaired work ability (1,139 conditions)

Related publications that referenced our studies

Loebl T, Raskin S, "A novel case report: acute manic psychotic episode after treatment with niacin", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .
Loebl T, Raskin S, "A novel case report: acute manic psychotic episode after treatment with niacin", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on niacin (the active ingredients of Niacin) and Niacin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.