Niacin and Mental disorder - a phase IV clinical study of FDA data

Summary:

Mental disorder is reported as a side effect among people who take Niacin (niacin), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Lipitor, and have Pain.

The phase IV clinical study analyzes which people have Mental disorder when taking Niacin. It is created by eHealthMe based on reports of 7,974 people who have side effects when taking Niacin from the FDA, and is updated regularly.

What is Niacin?

Niacin has active ingredients of niacin. It is often used in high blood cholesterol. eHealthMe is studying from 9,008 Niacin users. Check the latest studies of Niacin.

What is Mental disorder?

Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability) is found to be associated with 1,651 drugs and 1,713 conditions by eHealthMe. Check the latest studies of Mental disorder.



On Jul, 28, 2026

7,974 people reported to have side effects when taking Niacin.
Among them, 48 people (0.6%) have Mental disorder.

Could Niacin cause Mental disorder?

Among these 48 people:

How long have people been on Niacin when they have Mental disorder? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Mental disorder when taking Niacin? *

  • female: 53.33 %
  • male: 46.67 %

What is the age of people who have Mental disorder when taking Niacin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 4.55 %
  • 20-29: 0.0 %
  • 30-39: 4.55 %
  • 40-49: 6.82 %
  • 50-59: 20.45 %
  • 60+: 63.64 %

What are other drugs people take besides Niacin? *

  1. Lipitor: 28 people, 58.33%
  2. Effexor: 24 people, 50.00%
  3. Prozac: 24 people, 50.00%
  4. Roxicet: 20 people, 41.67%
  5. Ibuprofen: 19 people, 39.58%
  6. Folic Acid: 15 people, 31.25%
  7. Plavix: 15 people, 31.25%
  8. Amoxicillin: 15 people, 31.25%
  9. Xanax: 15 people, 31.25%
  10. Omeprazole: 15 people, 31.25%

What are other side effects people have besides Mental disorder? *

  1. Pain: 36 people, 75.00%
  2. Memory Loss: 25 people, 52.08%
  3. Neck Pain: 24 people, 50.00%
  4. Headache (pain in head): 23 people, 47.92%
  5. Back Pain: 22 people, 45.83%
  6. Injury: 21 people, 43.75%
  7. Spinal Osteoarthritis (joint cartilage loss in spine): 21 people, 43.75%
  8. Stress And Anxiety: 20 people, 41.67%
  9. Joint Pain: 20 people, 41.67%
  10. Depression: 19 people, 39.58%

What are the existing conditions these people have? *

  1. Pain: 14 people, 29.17%
  2. Prostate Cancer: 13 people, 27.08%
  3. Bone Density Abnormal: 13 people, 27.08%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 25.00%
  5. Osteoporosis (bones weak and more likely to break): 3 people, 6.25%
  6. Ovarian Cysts (fluid filled sacs of the ovary): 3 people, 6.25%
  7. Abdominal Pain: 3 people, 6.25%
  8. Acne (skin problems that cause pimples): 3 people, 6.25%
  9. Stress And Anxiety: 3 people, 6.25%
  10. Quit Smoking: 2 people, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Niacin and have Mental disorder?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Niacin:

Mental disorder treatments and more:

How severe was Mental disorder and when was it recovered:

Expand to all the drugs that have ingredients of niacin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Niacin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mental disorder:

Browse all the conditions that are associated with Mental disorder:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on niacin (the active ingredients of Niacin) and Niacin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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