Niaspan and Skin blushing/flushing - a phase IV clinical study of FDA data

Summary:

We study 44,388 people who have side effects when taking Niaspan. Skin blushing/flushing is found, especially among people who are male, 60+ old, have been taking the drug for < 1 month, also take Aspirin and have High density lipoprotein decreased.

The phase IV clinical study analyzes which people take Niaspan and have Skin blushing/flushing. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jul, 19, 2023

44,388 people reported to have side effects when taking Niaspan.
Among them, 18,900 people (42.58%) have Skin blushing/flushing.

What is Niaspan?

Niaspan has active ingredients of niacin. It is used in high blood cholesterol. Currently, eHealthMe is studying from 45,424 Niaspan users.

What is Skin blushing/flushing?

Skin blushing/flushing (a sudden reddening of the face, neck) is found to be associated with 3,533 drugs and 2,858 conditions by eHealthMe. Currently, we are studying 113,685 people who have Skin blushing/flushing.

Number of Niaspan and Skin blushing/flushing reports submitted per year:

Could Niaspan cause Skin blushing/flushing?

* Approximation only. Some reports may have incomplete information.

Do you take Niaspan and have Skin blushing/flushing?

Check whether Skin blushing/flushing is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Loebl T, Raskin S, "A novel case report: acute manic psychotic episode after treatment with niacin", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .

Related studies

Niaspan side effects by duration, gender and age:

Niaspan side effects (45,424 reports)

Skin blushing/flushing treatments and more:

Skin blushing/flushing (113,685 reports)

Common drugs associated with Skin blushing/flushing:

All the drugs that are associated with Skin blushing/flushing:

Skin blushing/flushing (3,533 drugs)

Common conditions associated with Skin blushing/flushing:

Multiple sclerosis: 20,241 reports
High blood cholesterol: 11,089 reports
Primary pulmonary hypertension: 5,307 reports
High blood pressure: 3,177 reports

All the conditions that are associated with Skin blushing/flushing:

Skin blushing/flushing (2,858 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on niacin (the active ingredients of Niaspan) and Niaspan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.