Nicorette and Chills - a phase IV clinical study of FDA data

Summary:

Chills is reported as a side effect among people who take Nicorette (nicotine polacrilex), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Aspirin, and have Pain.

The phase IV clinical study analyzes which people have Chills when taking Nicorette. It is created by eHealthMe based on reports of 18,337 people who have side effects when taking Nicorette from the FDA, and is updated regularly.

What is Nicorette?

Nicorette has active ingredients of nicotine polacrilex. It is often used in quit smoking. eHealthMe is studying from 18,484 Nicorette users. Check the latest studies of Nicorette.

What is Chills?

Chills (felling of cold) is found to be associated with 2,549 drugs and 3,475 conditions by eHealthMe. Check the latest studies of Chills.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

18,337 people reported to have side effects when taking Nicorette.
Among them, 21 people (0.11%) have Chills.

Among these 21 people:

How long have people been on Nicorette when they have Chills? *

What is the gender of people who have Chills when taking Nicorette? *

female: 52.63 %
male: 47.37 %

What is the age of people who have Chills when taking Nicorette? *

What are other drugs people take besides Nicorette? *

What are other side effects people have besides Chills? *

Fever: 6 people, 28.57%
Nausea (feeling of having an urge to vomit): 5 people, 23.81%
Diarrhea: 5 people, 23.81%
Hyperhidrosis (abnormally increased sweating): 4 people, 19.05%
Malaise (a feeling of general discomfort or uneasiness): 4 people, 19.05%
Gait Disturbance: 3 people, 14.29%
Muscle Aches (muscle pain): 3 people, 14.29%
Pain: 3 people, 14.29%
Headache (pain in head): 3 people, 14.29%
High Blood Pressure: 3 people, 14.29%

What are the existing conditions these people have? *

Pain: 3 people, 14.29%
Eyelid Oedema (eyelids are swollen and contain excessive fluid): 2 people, 9.52%
Endocrine Ophthalmopathy (increased water content of retroocular orbital tissues; associated with thyroid disease, usually hyperthyroidism): 2 people, 9.52%
Eye Pain: 2 people, 9.52%
Dry Eyes (lack of adequate tears): 2 people, 9.52%
Eyes - Bulging (swelling of eyes): 2 people, 9.52%
Hyperglycemia (high blood sugar): 2 people, 9.52%
Eye Inflammation: 2 people, 9.52%
Blepharitis (chronic inflammation of the eyelid): 2 people, 9.52%
Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Nicorette and have Chills?

- Check whether Chills is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nicorette:

Nicorette (18,484 reports)

Chills treatments and more:

Chills (145,628 reports)

Browse all side effects of Nicorette:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chills:

Chills (2,549 drugs)

Browse all the conditions that are associated with Chills:

Chills (3,475 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nicotine polacrilex (the active ingredients of Nicorette) and Nicorette (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.