Nicotine and Canker sores - a phase IV clinical study of FDA data

Summary:

Canker sores is reported as a side effect among people who take Nicotine (nicotine), especially for people who are female, 40-49 old, also take Hydrocortisone, and have Asthma.

The phase IV clinical study analyzes which people have Canker sores when taking Nicotine. It is created by eHealthMe based on reports of 20,079 people who have side effects when taking Nicotine from the FDA, and is updated regularly.

What is Nicotine?

Nicotine has active ingredients of nicotine. It is often used in quit smoking. eHealthMe is studying from 20,443 Nicotine users. Check the latest studies of Nicotine.

What is Canker sores?

Canker sores (painful, open sore in the mouth) is found to be associated with 613 drugs and 1,224 conditions by eHealthMe. Check the latest studies of Canker sores.



On Jul, 11, 2026

20,079 people reported to have side effects when taking Nicotine.
Among them, 12 people (0.06%) have Canker sores.

Could Nicotine cause Canker sores?

Among these 12 people:

What is the gender of people who have Canker sores when taking Nicotine? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Canker sores when taking Nicotine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 80 %
  • 50-59: 20 %
  • 60+: 0.0 %

What are other drugs people take besides Nicotine? *

  1. Acetaminophen: 6 people, 50.00%
  2. Albuterol: 6 people, 50.00%
  3. Azathioprine: 6 people, 50.00%
  4. Clonidine: 6 people, 50.00%
  5. Diazepam: 6 people, 50.00%
  6. Synthroid: 6 people, 50.00%
  7. Hydrocortisone: 6 people, 50.00%
  8. Valium: 5 people, 41.67%
  9. Inflectra: 5 people, 41.67%
  10. Opsumit: 3 people, 25.00%

What are other side effects people have besides Canker sores? *

  1. High Blood Pressure: 8 people, 66.67%
  2. Joint Pain: 6 people, 50.00%
  3. Psychotic Disorder: 6 people, 50.00%
  4. Drug Level Below Therapeutic: 6 people, 50.00%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 50.00%
  6. Poor Venous Access: 6 people, 50.00%
  7. Asthma: 6 people, 50.00%
  8. Food Poisoning (poison in food): 4 people, 33.33%
  9. The Flu (the flu is caused by an influenza virus): 3 people, 25.00%
  10. Nausea And Vomiting: 3 people, 25.00%

What are the existing conditions these people have? *

  1. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 50.00%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 50.00%
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 6 people, 50.00%
  4. Asthma: 6 people, 50.00%
  5. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 25.00%
  6. Dyspnea (difficult or laboured breathing): 3 people, 25.00%
  7. Panic Disorder: 2 people, 16.67%
  8. High Blood Pressure: 2 people, 16.67%
  9. Genital Herpes (herpes infection of genital): 2 people, 16.67%
  10. Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Nicotine and have Canker sores?

- Check whether Canker sores is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nicotine:

Canker sores treatments and more:

How severe was Canker sores and when was it recovered:

Expand to all the drugs that have ingredients of nicotine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nicotine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Canker sores:

Browse all the conditions that are associated with Canker sores:


How the study uses the data?

The study uses data from the FDA. It is based on nicotine (the active ingredients of Nicotine) and Nicotine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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