Nicotine and Hepatic enzyme increased - a phase IV clinical study of FDA data

Summary:

Hepatic enzyme increased is reported as a side effect among people who take Nicotine (nicotine), especially for people who are female, 30-39 old, also take Oxycontin, and have Birth control.

The phase IV clinical study analyzes which people have Hepatic enzyme increased when taking Nicotine. It is created by eHealthMe based on reports of 20,079 people who have side effects when taking Nicotine from the FDA, and is updated regularly.

What is Nicotine?

Nicotine has active ingredients of nicotine. It is often used in quit smoking. eHealthMe is studying from 20,443 Nicotine users. Check the latest studies of Nicotine.

What is Hepatic enzyme increased?

Hepatic enzyme increased is found to be associated with 1,885 drugs and 2,014 conditions by eHealthMe. Check the latest studies of Hepatic enzyme increased.



On Aug, 01, 2026

20,079 people reported to have side effects when taking Nicotine.
Among them, 29 people (0.14%) have Hepatic enzyme increased.

Could Nicotine cause Hepatic enzyme increased?

Among these 29 people:

What is the gender of people who have Hepatic enzyme increased when taking Nicotine? *

  • female: 88.89 %
  • male: 11.11 %

What is the age of people who have Hepatic enzyme increased when taking Nicotine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 8.33 %
  • 30-39: 50.0 %
  • 40-49: 12.5 %
  • 50-59: 8.33 %
  • 60+: 20.83 %

What are other drugs people take besides Nicotine? *

  1. Suboxone: 9 people, 31.03%
  2. Oxycontin: 9 people, 31.03%
  3. Subutex: 8 people, 27.59%
  4. Paxil Cr: 6 people, 20.69%
  5. Albuterol: 4 people, 13.79%
  6. Benadryl: 4 people, 13.79%
  7. Prilosec: 4 people, 13.79%
  8. Metronidazole: 4 people, 13.79%
  9. Zofran: 4 people, 13.79%
  10. Seroquel: 4 people, 13.79%

What are other side effects people have besides Hepatic enzyme increased? *

  1. Non-Alcoholic Steatohepatitis (liver inflammation caused by a build up of fat in the liver): 11 people, 37.93%
  2. Pre-Eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman): 11 people, 37.93%
  3. High Blood Pressure: 11 people, 37.93%
  4. Premature Delivery: 9 people, 31.03%
  5. Maternal Exposure During Pregnancy (use of substance during pregnancy): 6 people, 20.69%
  6. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 4 people, 13.79%
  7. Rashes (redness): 4 people, 13.79%
  8. Gallstones (stone formation by bile component): 3 people, 10.34%
  9. Nausea (feeling of having an urge to vomit): 3 people, 10.34%
  10. Cholecystitis (infection of gallbladder): 3 people, 10.34%

What are the existing conditions these people have? *

  1. Drug Dependence: 3 people, 10.34%
  2. Birth Control: 3 people, 10.34%
  3. Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 1 person, 3.45%
  4. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 3.45%
  5. Renal Cell Carcinoma (a kidney cancer): 1 person, 3.45%
  6. Psychotic Disorder: 1 person, 3.45%
  7. Pain: 1 person, 3.45%
  8. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 3.45%
  9. Myeloid Leukaemia (a type of cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 3.45%
  10. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Nicotine and have Hepatic enzyme increased?

- Check whether Hepatic enzyme increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nicotine:

Hepatic enzyme increased treatments and more:

How severe was Hepatic enzyme increased and when was it recovered:

Expand to all the drugs that have ingredients of nicotine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nicotine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic enzyme increased:

Browse all the conditions that are associated with Hepatic enzyme increased:


How the study uses the data?

The study uses data from the FDA. It is based on nicotine (the active ingredients of Nicotine) and Nicotine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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