Nicotine and Multi-organ failure - a phase IV clinical study of FDA data

Summary:

Multi-organ failure is reported as a side effect among people who take Nicotine (nicotine), especially for people who are female, 40-49 old, also take Fluticasone Propionate, and have Asthma.

The phase IV clinical study analyzes which people have Multi-organ failure when taking Nicotine. It is created by eHealthMe based on reports of 20,079 people who have side effects when taking Nicotine from the FDA, and is updated regularly.

What is Nicotine?

Nicotine has active ingredients of nicotine. It is often used in quit smoking. eHealthMe is studying from 20,443 Nicotine users. Check the latest studies of Nicotine.

What is Multi-organ failure?

Multi-organ failure (multisystem organ failure) is found to be associated with 1,389 drugs and 2,281 conditions by eHealthMe. Check the latest studies of Multi-organ failure.

On Aug, 08, 2026

20,079 people reported to have side effects when taking Nicotine.
Among them, 31 people (0.15%) have Multi-organ failure.

Could Nicotine cause Multi-organ failure?

Among these 31 people:

What is the gender of people who have Multi-organ failure when taking Nicotine? *

female: 54.84 %
male: 45.16 %

What is the age of people who have Multi-organ failure when taking Nicotine? *

What are other drugs people take besides Nicotine? *

Fluticasone Propionate: 7 people, 22.58%
Prednisone: 6 people, 19.35%
Temazepam: 6 people, 19.35%
Lasix: 6 people, 19.35%
Ativan: 5 people, 16.13%
Ondansetron Hydrochloride: 5 people, 16.13%
Acetaminophen: 5 people, 16.13%
Heparin: 5 people, 16.13%
Sodium Bicarbonate: 4 people, 12.90%
Famotidine: 4 people, 12.90%

What are other side effects people have besides Multi-organ failure? *

Hypotension (abnormally low blood pressure): 11 people, 35.48%
Sepsis (a severe blood infection that can lead to organ failure and death): 11 people, 35.48%
Acute Kidney Failure: 9 people, 29.03%
Pneumonia: 8 people, 25.81%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 6 people, 19.35%
Hepatic Failure (liver failure): 6 people, 19.35%
Dizziness: 5 people, 16.13%
Nausea And Vomiting: 5 people, 16.13%
Fever: 5 people, 16.13%
Abdominal Distension: 5 people, 16.13%

What are the existing conditions these people have? *

Asthma: 4 people, 12.90%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 9.68%
Lung Cancer - Non-Small Cell (lung cancer): 3 people, 9.68%
Fever: 3 people, 9.68%
Cough: 2 people, 6.45%
Dyspnea (difficult or laboured breathing): 2 people, 6.45%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 2 people, 6.45%
Renal Cell Carcinoma (a kidney cancer): 2 people, 6.45%
Nausea (feeling of having an urge to vomit): 2 people, 6.45%
Poor Quality Sleep: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Nicotine and have Multi-organ failure?

- Check whether Multi-organ failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nicotine:

Nicotine (20,443 reports)

Browse all side effects of Nicotine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multi-organ failure:

Multi-organ failure (1,389 drugs)

Browse all the conditions that are associated with Multi-organ failure:

Multi-organ failure (2,281 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nicotine (the active ingredients of Nicotine) and Nicotine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.