Nicotine and Multiple sclerosis relapse - a phase IV clinical study of FDA data

Summary:

Multiple sclerosis relapse is reported as a side effect among people who take Nicotine (nicotine), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Acetaminophen, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Multiple sclerosis relapse when taking Nicotine. It is created by eHealthMe based on reports of 20,079 people who have side effects when taking Nicotine from the FDA, and is updated regularly.

What is Nicotine?

Nicotine has active ingredients of nicotine. It is often used in quit smoking. eHealthMe is studying from 20,443 Nicotine users. Check the latest studies of Nicotine.

What is Multiple sclerosis relapse?

Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 1,030 drugs and 943 conditions by eHealthMe. Check the latest studies of Multiple sclerosis relapse.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

20,079 people reported to have side effects when taking Nicotine.
Among them, 50 people (0.25%) have Multiple sclerosis relapse.

Could Nicotine cause Multiple sclerosis relapse?

Among these 50 people:

How long have people been on Nicotine when they have Multiple sclerosis relapse? *

What is the gender of people who have Multiple sclerosis relapse when taking Nicotine? *

female: 90 %
male: 10 %

What is the age of people who have Multiple sclerosis relapse when taking Nicotine? *

What are other drugs people take besides Nicotine? *

What are other side effects people have besides Multiple sclerosis relapse? *

Urinary Tract Infection: 17 people, 34.00%
Headache (pain in head): 16 people, 32.00%
Fatigue (feeling of tiredness): 16 people, 32.00%
Fall: 16 people, 32.00%
Peripheral Swelling: 13 people, 26.00%
Dyspnea (difficult or laboured breathing): 13 people, 26.00%
Back Pain: 13 people, 26.00%
The Flu (the flu is caused by an influenza virus): 11 people, 22.00%
Dizziness: 11 people, 22.00%
Diarrhea: 10 people, 20.00%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 39 people, 78.00%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 11 people, 22.00%
Pain: 10 people, 20.00%
Depression: 7 people, 14.00%
Gait Disturbance: 6 people, 12.00%
Nausea (feeling of having an urge to vomit): 5 people, 10.00%
Headache (pain in head): 5 people, 10.00%
Indigestion: 5 people, 10.00%
Micturition Urgency (urgency to pass the urine): 4 people, 8.00%
Constipation: 4 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Nicotine and have Multiple sclerosis relapse?

- Check whether Multiple sclerosis relapse is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nicotine:

Nicotine (20,443 reports)

Browse all side effects of Nicotine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple sclerosis relapse:

Multiple sclerosis relapse (1,030 drugs)

Browse all the conditions that are associated with Multiple sclerosis relapse:

Multiple sclerosis relapse (943 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nicotine (the active ingredients of Nicotine) and Nicotine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.