Nifedipine and Chillblains - a phase IV clinical study of FDA data

Summary:

Chillblains is reported as a side effect among people who take Nifedipine (nifedipine), especially for people who are female, 10-19 old, also take Risperdal, and have Cutaneous lupus erythematosus.

The phase IV clinical study analyzes which people have Chillblains when taking Nifedipine. It is created by eHealthMe based on reports of 52,610 people who have side effects when taking Nifedipine from the FDA, and is updated regularly.

What is Nifedipine?

Nifedipine has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 53,459 Nifedipine users. Check the latest studies of Nifedipine.

What is Chillblains?

Chillblains (small, itchy swellings on the skin that occur as a reaction to cold) is found to be associated with 37 drugs and 101 conditions by eHealthMe. Check the latest studies of Chillblains.



On Jul, 30, 2026

52,610 people reported to have side effects when taking Nifedipine.
Among them, 12 people (0.02%) have Chillblains.

Could Nifedipine cause Chillblains?

Among these 12 people:

What is the gender of people who have Chillblains when taking Nifedipine? *

  • female: 90.91 %
  • male: 9.09 %

What is the age of people who have Chillblains when taking Nifedipine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 77.78 %
  • 20-29: 11.11 %
  • 30-39: 0.0 %
  • 40-49: 11.11 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Nifedipine? *

  1. Xanax: 9 people, 75.00%
  2. Thalidomide: 9 people, 75.00%
  3. Alprazolam: 9 people, 75.00%
  4. Aspirin: 9 people, 75.00%
  5. Duphalac: 9 people, 75.00%
  6. Acetaminophen: 9 people, 75.00%
  7. Risperdal: 9 people, 75.00%
  8. Plaquenil: 8 people, 66.67%
  9. Revlimid: 7 people, 58.33%
  10. Lenalidomide: 5 people, 41.67%

What are other side effects people have besides Chillblains? *

  1. Fatigue (feeling of tiredness): 10 people, 83.33%
  2. Frostbite (damage is caused to skin and other tissues due to freezing): 9 people, 75.00%
  3. Sleep Apnea Syndrome: 9 people, 75.00%
  4. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 9 people, 75.00%
  5. Memory Loss: 9 people, 75.00%
  6. Overdose: 9 people, 75.00%
  7. Hallucination, Auditory (perceiving sounds without auditory stimulus): 9 people, 75.00%
  8. Peripheral Coldness: 9 people, 75.00%
  9. Malaise (a feeling of general discomfort or uneasiness): 9 people, 75.00%
  10. Psychotic Disorder: 9 people, 75.00%

What are the existing conditions these people have? *

  1. Cutaneous Lupus Erythematosus (own immune system attacks various cells causing a wide variety of signs and symptoms): 3 people, 25.00%
  2. Psychotic Disorder: 2 people, 16.67%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 16.67%
  4. Suicide Attempt: 1 person, 8.33%
  5. Psoriasis (immune-mediated disease that affects the skin): 1 person, 8.33%
  6. Hypotension (abnormally low blood pressure): 1 person, 8.33%
  7. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 8.33%
  8. Bipolar Disorder (mood disorder): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Nifedipine and have Chillblains?

- Check whether Chillblains is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nifedipine:

Chillblains treatments and more:

How severe was Chillblains and when was it recovered:

Expand to all the drugs that have ingredients of nifedipine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nifedipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chillblains:

Browse all the conditions that are associated with Chillblains:


How the study uses the data?

The study uses data from the FDA. It is based on nifedipine (the active ingredients of Nifedipine) and Nifedipine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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