Nitrofurantoin and Enlarged prostate - a phase IV clinical study of FDA data

Summary:

Enlarged prostate is reported as a side effect among people who take Nitrofurantoin (nitrofurantoin, macrocrystalline), especially for people who are 60+ old, also take Ramipril, and have Depression.

The phase IV clinical study analyzes which people have Enlarged prostate when taking Nitrofurantoin. It is created by eHealthMe based on reports of 4,140 people who have side effects when taking Nitrofurantoin from the FDA, and is updated regularly.

What is Nitrofurantoin?

Nitrofurantoin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 4,837 Nitrofurantoin users. Check the latest studies of Nitrofurantoin.

What is Enlarged prostate?

Enlarged prostate is found to be associated with 842 drugs and 1,396 conditions by eHealthMe. Check the latest studies of Enlarged prostate.

On Apr, 18, 2026

4,140 people reported to have side effects when taking Nitrofurantoin.
Among them, 12 people (0.29%) have Enlarged prostate.

Could Nitrofurantoin cause Enlarged prostate?

Among these 12 people:

What is the age of people who have Enlarged prostate when taking Nitrofurantoin? *

What are other drugs people take besides Nitrofurantoin? *

Metoprolol Tartrate: 5 people, 41.67%
Simvastatin: 5 people, 41.67%
Warfarin Sodium: 5 people, 41.67%
Ramipril: 5 people, 41.67%
Lopid: 4 people, 33.33%
Levofloxacin: 4 people, 33.33%
Lasix: 4 people, 33.33%
Phenazopyridine Hcl Tab: 4 people, 33.33%
Zoloft: 4 people, 33.33%
Zolpidem Tartrate: 4 people, 33.33%

What are other side effects people have besides Enlarged prostate? *

Heart Attack: 7 people, 58.33%
Cardiac Failure Congestive: 6 people, 50.00%
Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 5 people, 41.67%
Prostatitis (inflammation of the prostate gland): 5 people, 41.67%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 5 people, 41.67%
Rosacea (a skin condition that causes facial redness): 4 people, 33.33%
Blepharitis (chronic inflammation of the eyelid): 4 people, 33.33%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 4 people, 33.33%
Stress And Anxiety: 4 people, 33.33%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 4 people, 33.33%

What are the existing conditions these people have? *

High Blood Cholesterol: 4 people, 33.33%
Depression: 4 people, 33.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 16.67%
Ill-Defined Disorder: 2 people, 16.67%
Type 2 Diabetes: 1 person, 8.33%
Nasopharyngitis (inflammation of the nasopharynx): 1 person, 8.33%
Guillain-Barre Syndrome (the body's immune system attacks its peripheral nervous system): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Nitrofurantoin and have Enlarged prostate?

- Check whether Enlarged prostate is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nitrofurantoin:

Nitrofurantoin (4,837 reports)

Enlarged prostate treatments and more:

Enlarged prostate (46,233 reports)

How severe was Enlarged prostate and when was it recovered:

Enlarged prostate in Nitrofurantoin

Expand to all the drugs that have ingredients of nitrofurantoin, macrocrystalline:

Enlarged prostate and drugs with ingredients of nitrofurantoin, macrocrystalline (13 reports)

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nitrofurantoin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Enlarged prostate:

Enlarged prostate (842 drugs)

Browse all the conditions that are associated with Enlarged prostate:

Enlarged prostate (1,396 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nitrofurantoin, macrocrystalline (the active ingredients of Nitrofurantoin) and Nitrofurantoin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.