Nitrofurantoin and Infection - a phase IV clinical study of FDA data

Summary:

Infection is reported as a side effect among people who take Nitrofurantoin (nitrofurantoin, macrocrystalline), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prednisone, and have Muscle spasms.

The phase IV clinical study analyzes which people have Infection when taking Nitrofurantoin. It is created by eHealthMe based on reports of 4,140 people who have side effects when taking Nitrofurantoin from the FDA, and is updated regularly.

What is Nitrofurantoin?

Nitrofurantoin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 4,838 Nitrofurantoin users. Check the latest studies of Nitrofurantoin.

What is Infection?

Infection is found to be associated with 2,499 drugs and 2,595 conditions by eHealthMe. Check the latest studies of Infection.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 19, 2026

4,140 people reported to have side effects when taking Nitrofurantoin.
Among them, 51 people (1.23%) have Infection.

Among these 51 people:

How long have people been on Nitrofurantoin when they have Infection? *

What is the gender of people who have Infection when taking Nitrofurantoin? *

female: 91.84 %
male: 8.16 %

What is the age of people who have Infection when taking Nitrofurantoin? *

What are other drugs people take besides Nitrofurantoin? *

What are other side effects people have besides Infection? *

Fall: 18 people, 35.29%
Pneumonia: 17 people, 33.33%
Pain: 16 people, 31.37%
Anaemia (lack of blood): 15 people, 29.41%
Back Pain: 15 people, 29.41%
Muscle Aches (muscle pain): 15 people, 29.41%
Neuropathy Peripheral (surface nerve damage): 15 people, 29.41%
Bone Disorder: 14 people, 27.45%
Osteomyelitis (infection of bone): 14 people, 27.45%
Cardiac Failure Congestive: 13 people, 25.49%

What are the existing conditions these people have? *

Pain: 7 people, 13.73%
Muscle Spasms (muscle contraction): 7 people, 13.73%
Psychotic Disorder: 5 people, 9.80%
Depression: 5 people, 9.80%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 3.92%
Birth Control: 2 people, 3.92%
Breast Cancer: 2 people, 3.92%
Escherichia Infection (bacterial infection by escherichia coli): 2 people, 3.92%
Type 2 Diabetes: 1 person, 1.96%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 1.96%

* Approximation only. Some reports may have incomplete information.

Do you take Nitrofurantoin and have Infection?

- Check whether Infection is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nitrofurantoin:

Nitrofurantoin (4,838 reports)

Infection treatments and more:

Infection (201,698 reports)

How severe was Infection and when was it recovered:

Infection in Nitrofurantoin

Expand to all the drugs that have ingredients of nitrofurantoin, macrocrystalline:

Infection and drugs with ingredients of nitrofurantoin, macrocrystalline

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nitrofurantoin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Infection:

Infection (2,499 drugs)

Browse all the conditions that are associated with Infection:

Infection (2,595 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nitrofurantoin, macrocrystalline (the active ingredients of Nitrofurantoin) and Nitrofurantoin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.