Norflex and Obsessive-compulsive disorder - a phase IV clinical study of FDA data

Summary:

Obsessive-compulsive disorder is reported as a side effect among people who take Norflex (orphenadrine citrate), especially for people who are male, 40-49 old, have been taking the drug for 2 - 5 years also take Vioxx, and have High blood pressure.

The phase IV clinical study analyzes which people have Obsessive-compulsive disorder when taking Norflex. It is created by eHealthMe based on reports of 1,749 people who have side effects when taking Norflex from the FDA, and is updated regularly.

What is Norflex?

Norflex has active ingredients of orphenadrine citrate. It is often used in muscle spasms. eHealthMe is studying from 1,951 Norflex users. Check the latest studies of Norflex.

What is Obsessive-compulsive disorder?

Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;) is found to be associated with 679 drugs and 1,311 conditions by eHealthMe. Check the latest studies of Obsessive-compulsive disorder.

On Jul, 20, 2026

1,749 people reported to have side effects when taking Norflex.
Among them, 11 people (0.63%) have Obsessive-compulsive disorder.

Could Norflex cause Obsessive-compulsive disorder?

Among these 11 people:

How long have people been on Norflex when they have Obsessive-compulsive disorder? *

What is the gender of people who have Obsessive-compulsive disorder when taking Norflex? *

female: 45.45 %
male: 54.55 %

What is the age of people who have Obsessive-compulsive disorder when taking Norflex? *

What are other drugs people take besides Norflex? *

What are other side effects people have besides Obsessive-compulsive disorder? *

Pain: 10 people, 90.91%
Stress And Anxiety: 10 people, 90.91%
Depression: 9 people, 81.82%
Abdominal Pain: 6 people, 54.55%
Decreased Interest: 6 people, 54.55%
Insomnia (sleeplessness): 6 people, 54.55%
Pain In Extremity: 6 people, 54.55%
Emotional Distress: 6 people, 54.55%
Dyspnea (difficult or laboured breathing): 6 people, 54.55%
Joint Pain: 6 people, 54.55%

What are the existing conditions these people have? *

Parkinson's Disease: 5 people, 45.45%
Pain: 5 people, 45.45%
High Blood Pressure: 5 people, 45.45%
Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other): 4 people, 36.36%
Depression: 4 people, 36.36%
Constipation: 2 people, 18.18%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Norflex and have Obsessive-compulsive disorder?

- Check whether Obsessive-compulsive disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Norflex:

Norflex (1,951 reports)

Browse all side effects of Norflex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Obsessive-compulsive disorder:

Obsessive-compulsive disorder (679 drugs)

Browse all the conditions that are associated with Obsessive-compulsive disorder:

Obsessive-compulsive disorder (1,311 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on orphenadrine citrate (the active ingredients of Norflex) and Norflex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.