Northera and Intestinal obstruction - a phase IV clinical study of FDA data

Summary:

Intestinal obstruction is reported as a side effect among people who take Northera (droxidopa), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Protonix, and have Orthostatic hypotension.

The phase IV clinical study analyzes which people have Intestinal obstruction when taking Northera. It is created by eHealthMe based on reports of 22,868 people who have side effects when taking Northera from the FDA, and is updated regularly.

What is Northera?

Northera has active ingredients of droxidopa. eHealthMe is studying from 22,874 Northera users. Check the latest studies of Northera.

What is Intestinal obstruction?

Intestinal obstruction is found to be associated with 1,887 drugs and 2,613 conditions by eHealthMe. Check the latest studies of Intestinal obstruction.

On Jul, 13, 2026

22,868 people reported to have side effects when taking Northera.
Among them, 18 people (0.08%) have Intestinal obstruction.

Could Northera cause Intestinal obstruction?

Among these 18 people:

How long have people been on Northera when they have Intestinal obstruction? *

What is the gender of people who have Intestinal obstruction when taking Northera? *

female: 44.44 %
male: 55.56 %

What is the age of people who have Intestinal obstruction when taking Northera? *

What are other drugs people take besides Northera? *

What are other side effects people have besides Intestinal obstruction? *

Diarrhea: 3 people, 16.67%
Adrenocortical Insufficiency Acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones): 2 people, 11.11%
Arrhythmias (irregular heartbeat): 2 people, 11.11%
Small Intestinal Obstruction (blockage in small intestine): 2 people, 11.11%
Blood Pressure Fluctuation: 2 people, 11.11%
Infusion Site Extravasation (flow of (blood or lymph) from infusion site): 2 people, 11.11%
Urinary Tract Infection: 2 people, 11.11%
Urination - Painful: 1 person, 5.56%
Functional Gastrointestinal Disorder (functional problem in separate organs of gastrointestinal system): 1 person, 5.56%
Adverse Event: 1 person, 5.56%

What are the existing conditions these people have? *

Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 10 people, 55.56%
Parkinson's Disease: 8 people, 44.44%
Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 3 people, 16.67%
High Blood Cholesterol: 2 people, 11.11%
Immunodeficiency Common Variable: 2 people, 11.11%
Hypotension (abnormally low blood pressure): 2 people, 11.11%
Orthostatic Intolerance (development of symptoms when standing upright which are relieved when sitting back down again): 1 person, 5.56%
Muscle Spasms (muscle contraction): 1 person, 5.56%
Pain: 1 person, 5.56%
Prostatic Disorder: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Northera and have Intestinal obstruction?

- Check whether Intestinal obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Northera:

Northera (22,874 reports)

Browse all side effects of Northera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intestinal obstruction:

Intestinal obstruction (1,887 drugs)

Browse all the conditions that are associated with Intestinal obstruction:

Intestinal obstruction (2,613 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on droxidopa (the active ingredients of Northera) and Northera (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.