Norvasc and Astigmatism - a phase IV clinical study of FDA data

Summary:

Astigmatism is reported as a side effect among people who take Norvasc (amlodipine besylate), especially for people who are male, 60+ old, have been taking the drug for 10+ years also take Atenolol, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Astigmatism when taking Norvasc. It is created by eHealthMe based on reports of 133,505 people who have side effects when taking Norvasc from the FDA, and is updated regularly.

What is Norvasc?

Norvasc has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 136,738 Norvasc users. Check the latest studies of Norvasc.

What is Astigmatism?

Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina) is found to be associated with 363 drugs and 421 conditions by eHealthMe. Check the latest studies of Astigmatism.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

133,505 people reported to have side effects when taking Norvasc.
Among them, 64 people (0.05%) have Astigmatism.

Among these 64 people:

How long have people been on Norvasc when they have Astigmatism? *

What is the gender of people who have Astigmatism when taking Norvasc? *

female: 34.38 %
male: 65.62 %

What is the age of people who have Astigmatism when taking Norvasc? *

What are other drugs people take besides Norvasc? *

What are other side effects people have besides Astigmatism? *

Weakness: 42 people, 65.62%
Osteomyelitis (infection of bone): 39 people, 60.94%
Back Pain: 37 people, 57.81%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 37 people, 57.81%
Swallowing Difficulty: 36 people, 56.25%
Osteonecrosis Of Jaw (death of bone of jaw): 36 people, 56.25%
Aortic Aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall): 36 people, 56.25%
Plasmacytosis (presence of lots of plasma cells in bone or other tissues): 36 people, 56.25%
Hypermetropia (abnormal condition in which vision for distant objects is better than for near objects): 35 people, 54.69%
Intervertebral Disc Degeneration (spinal disc degeneration): 35 people, 54.69%

What are the existing conditions these people have? *

Pain: 27 people, 42.19%
Multiple Myeloma (cancer of the plasma cells): 27 people, 42.19%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 10 people, 15.62%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 3 people, 4.69%
Osteoporosis (bones weak and more likely to break): 2 people, 3.12%
Neuropathy Peripheral (surface nerve damage): 2 people, 3.12%
Blood Parathyroid Hormone Increased: 2 people, 3.12%
Depression: 2 people, 3.12%
Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other): 1 person, 1.56%
Acute Upper Airway Obstruction (blockage occurs in the upper airway): 1 person, 1.56%

* Approximation only. Some reports may have incomplete information.

Do you take Norvasc and have Astigmatism?

- Check whether Astigmatism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Norvasc:

Norvasc (136,738 reports)

Astigmatism treatments and more:

Astigmatism (2,086 reports)

Browse all side effects of Norvasc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Astigmatism:

Astigmatism (363 drugs)

Browse all the conditions that are associated with Astigmatism:

Astigmatism (421 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Norvasc) and Norvasc (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.