Norvasc and Corneal opacity - a phase IV clinical study of FDA data

Summary:

Corneal opacity is reported as a side effect among people who take Norvasc (amlodipine besylate), especially for people who are male, 60+ old, also take Atenolol, and have Streptococcal infection.

The phase IV clinical study analyzes which people have Corneal opacity when taking Norvasc. It is created by eHealthMe based on reports of 133,505 people who have side effects when taking Norvasc from the FDA, and is updated regularly.

What is Norvasc?

Norvasc has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 136,738 Norvasc users. Check the latest studies of Norvasc.

What is Corneal opacity?

Corneal opacity (scarring or clouding of the cornea) is found to be associated with 126 drugs and 314 conditions by eHealthMe. Check the latest studies of Corneal opacity.



On Jul, 16, 2026

133,505 people reported to have side effects when taking Norvasc.
Among them, 15 people (0.01%) have Corneal opacity.

Could Norvasc cause Corneal opacity?

Among these 15 people:

What is the gender of people who have Corneal opacity when taking Norvasc? *

  • female: 38.46 %
  • male: 61.54 %

What is the age of people who have Corneal opacity when taking Norvasc? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 16.67 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 16.67 %
  • 60+: 66.67 %

What are other drugs people take besides Norvasc? *

  1. Atenolol: 8 people, 53.33%
  2. Coumadin: 6 people, 40.00%
  3. Zometa: 4 people, 26.67%
  4. Selenium: 4 people, 26.67%
  5. Glipizide: 4 people, 26.67%
  6. Gabapentin: 4 people, 26.67%
  7. Flomax: 4 people, 26.67%
  8. Metformin Hydrochloride: 4 people, 26.67%
  9. Novolog: 4 people, 26.67%
  10. Torsemide: 4 people, 26.67%

What are other side effects people have besides Corneal opacity? *

  1. Pain: 7 people, 46.67%
  2. Fatigue (feeling of tiredness): 7 people, 46.67%
  3. Swallowing Difficulty: 6 people, 40.00%
  4. Dyspnea (difficult or laboured breathing): 5 people, 33.33%
  5. Urinary Tract Infection: 5 people, 33.33%
  6. Oedema Peripheral (superficial swelling): 5 people, 33.33%
  7. Injury: 5 people, 33.33%
  8. Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 33.33%
  9. Fever: 4 people, 26.67%
  10. Fungal Nail Infection: 4 people, 26.67%

What are the existing conditions these people have? *

  1. Streptococcal Infection: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Norvasc and have Corneal opacity?

- Check whether Corneal opacity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Norvasc:

Corneal opacity treatments and more:

How severe was Corneal opacity and when was it recovered:

Expand to all the drugs that have ingredients of amlodipine besylate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Norvasc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Corneal opacity:

Browse all the conditions that are associated with Corneal opacity:


How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Norvasc) and Norvasc (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: