Norvasc and Rectal ulcer - a phase IV clinical study of FDA data

Summary:

Rectal ulcer is reported as a side effect among people who take Norvasc (amlodipine besylate), especially for people who are male, 60+ old, have been taking the drug for 10+ years also take Lasix, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Rectal ulcer when taking Norvasc. It is created by eHealthMe based on reports of 133,505 people who have side effects when taking Norvasc from the FDA, and is updated regularly.

What is Norvasc?

Norvasc has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 136,738 Norvasc users. Check the latest studies of Norvasc.

What is Rectal ulcer?

Rectal ulcer (ulcer of rectum) is found to be associated with 227 drugs and 397 conditions by eHealthMe. Check the latest studies of Rectal ulcer.

On Jul, 20, 2026

133,505 people reported to have side effects when taking Norvasc.
Among them, 17 people (0.01%) have Rectal ulcer.

Among these 17 people:

How long have people been on Norvasc when they have Rectal ulcer? *

What is the gender of people who have Rectal ulcer when taking Norvasc? *

female: 35.29 %
male: 64.71 %

What is the age of people who have Rectal ulcer when taking Norvasc? *

What are other drugs people take besides Norvasc? *

What are other side effects people have besides Rectal ulcer? *

Dehydration (dryness resulting from the removal of water): 3 people, 17.65%
Anaemia (lack of blood): 3 people, 17.65%
Perianal Abscess: 2 people, 11.76%
Aspartate Aminotransferase Increased: 2 people, 11.76%
Joint Pain: 2 people, 11.76%
Melaena (the passage of black, tarry stools): 2 people, 11.76%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 2 people, 11.76%
Cardiac Failure Congestive: 2 people, 11.76%
Blood Urea Increased: 2 people, 11.76%
International Normalised Ratio Increased: 2 people, 11.76%

What are the existing conditions these people have? *

Nephrogenic Anaemia (anaemia due to kidney disease): 3 people, 17.65%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 17.65%
Nephrosclerosis (hardening of the kidney due to renovascular disease): 2 people, 11.76%
Insomnia (sleeplessness): 2 people, 11.76%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.88%
Reflux Oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus): 1 person, 5.88%
Prostate Cancer Metastatic: 1 person, 5.88%
Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 1 person, 5.88%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 1 person, 5.88%
Hepatitis C: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Norvasc and have Rectal ulcer?

- Check whether Rectal ulcer is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Norvasc:

Norvasc (136,738 reports)

Rectal ulcer treatments and more:

Rectal ulcer (1,614 reports)

Browse all side effects of Norvasc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rectal ulcer:

Rectal ulcer (227 drugs)

Browse all the conditions that are associated with Rectal ulcer:

Rectal ulcer (397 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Norvasc) and Norvasc (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.