Norvasc and Svc obstruction - a phase IV clinical study of FDA data
Summary:
Svc obstruction is reported as a side effect among people who take Norvasc (amlodipine besylate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Prilosec, and have Hypothyroidism.
The phase IV clinical study analyzes which people have Svc obstruction when taking Norvasc. It is created by eHealthMe based on reports of 133,505 people who have side effects when taking Norvasc from the FDA, and is updated regularly.
What is Norvasc?
Norvasc has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 136,738 Norvasc users. Check the latest studies of Norvasc.
What is Svc obstruction?
Svc obstruction (superior vena cava obstruction (svco) is an uncommon complication of lung cancer) is found to be associated with 213 drugs and 339 conditions by eHealthMe. Check the latest studies of Svc obstruction.
133,505 people reported to have side effects when taking Norvasc.
Among them, 13 people (0.01%) have Svc obstruction.

Among these 13 people:
How long have people been on Norvasc when they have Svc obstruction? *
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Svc obstruction when taking Norvasc? *
- female: 23.08 %
- male: 76.92 %
What is the age of people who have Svc obstruction when taking Norvasc? *
- 0-1: 8.33 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 8.33 %
- 40-49: 0.0 %
- 50-59: 8.33 %
- 60+: 75.0 %
What are other drugs people take besides Norvasc? *
- Prilosec: 11 people, 84.62%
- Coumadin: 10 people, 76.92%
- Zofran: 10 people, 76.92%
- Zometa: 9 people, 69.23%
- Compazine: 9 people, 69.23%
- Lovenox: 8 people, 61.54%
- Folic Acid: 8 people, 61.54%
- Neurontin: 8 people, 61.54%
- Protonix: 8 people, 61.54%
- Lomotil: 8 people, 61.54%
What are other side effects people have besides Svc obstruction? *
- Pain: 11 people, 84.62%
- Dyspnea (difficult or laboured breathing): 11 people, 84.62%
- Abdominal Pain: 10 people, 76.92%
- Injury: 10 people, 76.92%
- Gallstones (stone formation by bile component): 10 people, 76.92%
- Oedema Peripheral (superficial swelling): 10 people, 76.92%
- Rashes (redness): 10 people, 76.92%
- Atelectasis (partial or complete collapse of the lung): 10 people, 76.92%
- Anaemia (lack of blood): 10 people, 76.92%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 10 people, 76.92%
What are the existing conditions these people have? *
- Breast Cancer Metastatic: 2 people, 15.38%
- Pain: 2 people, 15.38%
- High Blood Cholesterol: 2 people, 15.38%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 15.38%
- Wheezing (a high-pitched whistling sound made while you breath): 1 person, 7.69%
- Indigestion: 1 person, 7.69%
- Agitation (state of anxiety or nervous excitement): 1 person, 7.69%
- Asthma: 1 person, 7.69%
- Body Temperature Increased: 1 person, 7.69%
- Constipation: 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Norvasc and have Svc obstruction?
- Check whether Svc obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Norvasc:
- Norvasc (136,738 reports)
Svc obstruction treatments and more:
- Svc obstruction (916 reports)
How severe was Svc obstruction and when was it recovered:
Expand to all the drugs that have ingredients of amlodipine besylate:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Norvasc:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Svc obstruction:
- Svc obstruction (213 drugs)
Browse all the conditions that are associated with Svc obstruction:
- Svc obstruction (339 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Norvasc) and Norvasc (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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