Novantrone and Oral discharge - a phase IV clinical study of FDA data

Summary:

Oral discharge is reported as a side effect among people who take Novantrone (mitoxantrone hydrochloride), especially for people who are female, 40-49 old, also take Aredia, and have Chronic thyroiditis.

The phase IV clinical study analyzes which people have Oral discharge when taking Novantrone. It is created by eHealthMe based on reports of 3,338 people who have side effects when taking Novantrone from the FDA, and is updated regularly.

What is Novantrone?

Novantrone has active ingredients of mitoxantrone hydrochloride. It is often used in multiple sclerosis. eHealthMe is studying from 3,349 Novantrone users. Check the latest studies of Novantrone.

What is Oral discharge?

Oral discharge is found to be associated with 169 drugs and 171 conditions by eHealthMe. Check the latest studies of Oral discharge.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

3,338 people reported to have side effects when taking Novantrone.
Among them, 20 people (0.6%) have Oral discharge.

Could Novantrone cause Oral discharge?

Among these 20 people:

What is the gender of people who have Oral discharge when taking Novantrone? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Oral discharge when taking Novantrone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 5.26 %
  • 40-49: 94.74 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Novantrone? *

  1. Zometa: 20 people, 100.00%
  2. Aredia: 20 people, 100.00%
  3. Taxol: 19 people, 95.00%
  4. Herceptin: 19 people, 95.00%
  5. Femara: 19 people, 95.00%
  6. Cytoxan: 19 people, 95.00%
  7. Synthroid: 19 people, 95.00%
  8. Nolvadex: 19 people, 95.00%
  9. Aromasin: 19 people, 95.00%
  10. Thiotepa: 18 people, 90.00%

What are other side effects people have besides Oral discharge? *

  1. Actinomycosis (infection that causes sores, or abscesses): 20 people, 100.00%
  2. Rashes (redness): 20 people, 100.00%
  3. Fatigue (feeling of tiredness): 20 people, 100.00%
  4. Osteomyelitis (infection of bone): 20 people, 100.00%
  5. Stress And Anxiety: 20 people, 100.00%
  6. Swelling: 20 people, 100.00%
  7. Tooth Abscess (pus formation in tooth): 20 people, 100.00%
  8. Anaemia (lack of blood): 20 people, 100.00%
  9. Primary Sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone): 20 people, 100.00%
  10. High Blood Pressure: 19 people, 95.00%

What are the existing conditions these people have? *

  1. Chronic Thyroiditis (long lasting inflammation of thyroid gland): 19 people, 95.00%
  2. Stress And Anxiety: 17 people, 85.00%
  3. Metastases To Bone (cancer spreads to bone): 14 people, 70.00%
  4. Breast Cancer: 13 people, 65.00%
  5. Prostate Cancer Metastatic: 1 person, 5.00%
  6. Osteoporosis (bones weak and more likely to break): 1 person, 5.00%
  7. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Novantrone and have Oral discharge?

- Check whether Oral discharge is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Novantrone:

Oral discharge treatments and more:

How severe was Oral discharge and when was it recovered:

Expand to all the drugs that have ingredients of mitoxantrone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Novantrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oral discharge:

Browse all the conditions that are associated with Oral discharge:


How the study uses the data?

The study uses data from the FDA. It is based on mitoxantrone hydrochloride (the active ingredients of Novantrone) and Novantrone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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