Noxafil and Malaise - a phase IV clinical study of FDA data

Summary:

Malaise is reported as a side effect among people who take Noxafil (posaconazole), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Bactrim, and have Acute myeloid leukaemia.

The phase IV clinical study analyzes which people have Malaise when taking Noxafil. It is created by eHealthMe based on reports of 5,902 people who have side effects when taking Noxafil from the FDA, and is updated regularly.

What is Noxafil?

Noxafil has active ingredients of posaconazole. eHealthMe is studying from 5,919 Noxafil users. Check the latest studies of Noxafil.

What is Malaise?

Malaise (a feeling of general discomfort or uneasiness) is found to be associated with 3,499 drugs and 5,120 conditions by eHealthMe. Check the latest studies of Malaise.



On Jul, 28, 2026

5,902 people reported to have side effects when taking Noxafil.
Among them, 68 people (1.15%) have Malaise.

Could Noxafil cause Malaise?

Among these 68 people:

How long have people been on Noxafil when they have Malaise? *

  • < 1 month: 42.86 %
  • 1 - 6 months: 42.86 %
  • 6 - 12 months: 14.29 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Malaise when taking Noxafil? *

  • female: 40.32 %
  • male: 59.68 %

What is the age of people who have Malaise when taking Noxafil? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 6.25 %
  • 20-29: 4.17 %
  • 30-39: 14.58 %
  • 40-49: 14.58 %
  • 50-59: 18.75 %
  • 60+: 41.67 %

What are other drugs people take besides Noxafil? *

  1. Bactrim: 9 people, 13.24%
  2. Zofran: 8 people, 11.76%
  3. Pantoprazole: 8 people, 11.76%
  4. Vitamin D3: 8 people, 11.76%
  5. Magnesium: 8 people, 11.76%
  6. Cellcept: 6 people, 8.82%
  7. Ursodeoxycholic Acid: 6 people, 8.82%
  8. Acyclovir: 6 people, 8.82%
  9. Vancomycin: 6 people, 8.82%
  10. Adderall: 5 people, 7.35%

What are other side effects people have besides Malaise? *

  1. Fever: 13 people, 19.12%
  2. Fatigue (feeling of tiredness): 11 people, 16.18%
  3. Thrombocytopenia (decrease of platelets in blood): 7 people, 10.29%
  4. Anaemia (lack of blood): 7 people, 10.29%
  5. Death: 6 people, 8.82%
  6. Joint Pain: 6 people, 8.82%
  7. Rashes (redness): 6 people, 8.82%
  8. Weakness: 6 people, 8.82%
  9. Staphylococcal Infection (an infection with staphylococcus bacteria): 6 people, 8.82%
  10. Febrile Bone Marrow Aplasia (bone marrow greatly decreases or stops production of blood cells): 5 people, 7.35%

What are the existing conditions these people have? *

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 12 people, 17.65%
  2. High Blood Pressure: 6 people, 8.82%
  3. Anaemia (lack of blood): 6 people, 8.82%
  4. Hypouricaemia (level of uric acid in the blood that is abnormally high): 5 people, 7.35%
  5. Cardiac Disorder: 5 people, 7.35%
  6. Hyperchlorhydria (gastric acid levels are higher in stomach): 5 people, 7.35%
  7. Cough: 5 people, 7.35%
  8. High Blood Cholesterol: 5 people, 7.35%
  9. Fungal Infection: 5 people, 7.35%
  10. Pneumonia Viral: 5 people, 7.35%

* Approximation only. Some reports may have incomplete information.

Do you take Noxafil and have Malaise?

- Check whether Malaise is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Noxafil:

Malaise treatments and more:

How severe was Malaise and when was it recovered:

Expand to all the drugs that have ingredients of posaconazole:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Noxafil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Malaise:

Browse all the conditions that are associated with Malaise:


How the study uses the data?

The study uses data from the FDA. It is based on posaconazole (the active ingredients of Noxafil) and Noxafil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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