Nubain and Chest pain - a phase IV clinical study of FDA data

Summary:

Chest pain is reported as a side effect among people who take Nubain (nalbuphine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Toradol, and have Migraine.

The phase IV clinical study analyzes which people have Chest pain when taking Nubain. It is created by eHealthMe based on reports of 1,718 people who have side effects when taking Nubain from the FDA, and is updated regularly.

What is Nubain?

Nubain has active ingredients of nalbuphine hydrochloride. It is often used in pain. eHealthMe is studying from 1,749 Nubain users. Check the latest studies of Nubain.

What is Chest pain?

Chest pain is found to be associated with 3,469 drugs and 4,888 conditions by eHealthMe. Check the latest studies of Chest pain.

On Jul, 12, 2026

1,718 people reported to have side effects when taking Nubain.
Among them, 49 people (2.85%) have Chest pain.

Among these 49 people:

How long have people been on Nubain when they have Chest pain? *

What is the gender of people who have Chest pain when taking Nubain? *

female: 61.22 %
male: 38.78 %

What is the age of people who have Chest pain when taking Nubain? *

What are other drugs people take besides Nubain? *

What are other side effects people have besides Chest pain? *

Dyspnea (difficult or laboured breathing): 17 people, 34.69%
Nausea (feeling of having an urge to vomit): 15 people, 30.61%
Fatigue (feeling of tiredness): 15 people, 30.61%
Weakness: 13 people, 26.53%
Sinusitis (inflammation of sinus): 13 people, 26.53%
Injury: 12 people, 24.49%
High Blood Pressure: 11 people, 22.45%
Dizziness: 11 people, 22.45%
Headache (pain in head): 10 people, 20.41%
Agitation (state of anxiety or nervous excitement): 10 people, 20.41%

What are the existing conditions these people have? *

Back Pain: 4 people, 8.16%
Migraine (headache): 4 people, 8.16%
Acute Myocardial Infarction (acute heart attack): 3 people, 6.12%
Depression: 3 people, 6.12%
Headache (pain in head): 2 people, 4.08%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 4.08%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 4.08%
Anaesthesia: 1 person, 2.04%
Asthma: 1 person, 2.04%
Atrioventricular Block Complete (heart block complete): 1 person, 2.04%

* Approximation only. Some reports may have incomplete information.

Do you take Nubain and have Chest pain?

- Check whether Chest pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nubain:

Nubain (1,749 reports)

Chest pain treatments and more:

Chest pain (363,501 reports)

Browse all side effects of Nubain:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chest pain:

Chest pain (3,469 drugs)

Browse all the conditions that are associated with Chest pain:

Chest pain (4,888 conditions)

Related publications that referenced our studies

Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .
Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on nalbuphine hydrochloride (the active ingredients of Nubain) and Nubain (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.