Nucynta er and Swallowing difficulty - a phase IV clinical study of FDA data

Summary:

Swallowing difficulty is reported as a side effect among people who take Nucynta er (tapentadol hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lyrica, and have Hypersensitivity.

The phase IV clinical study analyzes which people have Swallowing difficulty when taking Nucynta er. It is created by eHealthMe based on reports of 2,418 people who have side effects when taking Nucynta er from the FDA, and is updated regularly.

What is Nucynta er?

Nucynta er has active ingredients of tapentadol hydrochloride. It is often used in pain. eHealthMe is studying from 2,508 Nucynta er users. Check the latest studies of Nucynta er.

What is Swallowing difficulty?

Swallowing difficulty is found to be associated with 2,401 drugs and 3,349 conditions by eHealthMe. Check the latest studies of Swallowing difficulty.

On Jul, 14, 2026

2,418 people reported to have side effects when taking Nucynta er.
Among them, 33 people (1.36%) have Swallowing difficulty.

Could Nucynta er cause Swallowing difficulty?

Among these 33 people:

How long have people been on Nucynta er when they have Swallowing difficulty? *

What is the gender of people who have Swallowing difficulty when taking Nucynta er? *

female: 47.83 %
male: 52.17 %

What is the age of people who have Swallowing difficulty when taking Nucynta er? *

What are other drugs people take besides Nucynta er? *

Percocet: 5 people, 15.15%
Nucynta: 5 people, 15.15%
Lyrica: 5 people, 15.15%
Acetaminophen: 4 people, 12.12%
Fentanyl Citrate: 3 people, 9.09%
Tramadol Hydrochloride: 3 people, 9.09%
Opana Er: 3 people, 9.09%
Diphenhydramine Hydrochloride: 3 people, 9.09%
Cymbalta: 2 people, 6.06%
Hydrocortisone Valerate: 2 people, 6.06%

What are other side effects people have besides Swallowing difficulty? *

Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 8 people, 24.24%
Drug Withdrawal Syndrome Neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother): 8 people, 24.24%
Nausea (feeling of having an urge to vomit): 6 people, 18.18%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 18.18%
Depression: 4 people, 12.12%
Fatigue (feeling of tiredness): 4 people, 12.12%
Developmental Delay: 4 people, 12.12%
Visual Impairment: 4 people, 12.12%
Asthma: 4 people, 12.12%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 4 people, 12.12%

What are the existing conditions these people have? *

Hypersensitivity: 3 people, 9.09%
Thyroid Diseases: 2 people, 6.06%
Asthma: 2 people, 6.06%
Breakthrough Pain: 2 people, 6.06%
Cancer Pain: 2 people, 6.06%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 6.06%
High Blood Pressure: 2 people, 6.06%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.06%
Sleep Disorder: 2 people, 6.06%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Nucynta er and have Swallowing difficulty?

- Check whether Swallowing difficulty is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nucynta er:

Nucynta er (2,508 reports)

Browse all side effects of Nucynta er:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Swallowing difficulty:

Swallowing difficulty (2,401 drugs)

Browse all the conditions that are associated with Swallowing difficulty:

Swallowing difficulty (3,349 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tapentadol hydrochloride (the active ingredients of Nucynta er) and Nucynta er (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.