Nuvaring and Left ventricular dysfunction - a phase IV clinical study of FDA data

Summary:

Left ventricular dysfunction is reported as a side effect among people who take Nuvaring (ethinyl estradiol; etonogestrel), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Nexium, and have Weight loss.

The phase IV clinical study analyzes which people have Left ventricular dysfunction when taking Nuvaring. It is created by eHealthMe based on reports of 27,664 people who have side effects when taking Nuvaring from the FDA, and is updated regularly.

What is Nuvaring?

Nuvaring has active ingredients of ethinyl estradiol; etonogestrel. It is often used in birth control. eHealthMe is studying from 28,729 Nuvaring users. Check the latest studies of Nuvaring.

What is Left ventricular dysfunction?

Left ventricular dysfunction is found to be associated with 916 drugs and 792 conditions by eHealthMe. Check the latest studies of Left ventricular dysfunction.



On Feb, 08, 2026

27,664 people reported to have side effects when taking Nuvaring.
Among them, 31 people (0.11%) have Left ventricular dysfunction.

Could Nuvaring cause Left ventricular dysfunction?

Among these 31 people:

How long have people been on Nuvaring when they have Left ventricular dysfunction? *

  • < 1 month: 35.29 %
  • 1 - 6 months: 23.53 %
  • 6 - 12 months: 35.29 %
  • 1 - 2 years: 5.88 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Left ventricular dysfunction when taking Nuvaring? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Left ventricular dysfunction when taking Nuvaring? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 72.73 %
  • 30-39: 9.09 %
  • 40-49: 18.18 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Nuvaring? *

  1. Nexium: 10 people, 32.26%
  2. Ortho Evra: 3 people, 9.68%
  3. Levothyroxine Sodium: 2 people, 6.45%
  4. Albuterol: 2 people, 6.45%
  5. Vicodin: 2 people, 6.45%
  6. Ventolin Hfa: 1 person, 3.23%
  7. Lithium Citrate: 1 person, 3.23%
  8. Axert: 1 person, 3.23%
  9. Celebrex: 1 person, 3.23%
  10. Celexa: 1 person, 3.23%

What are other side effects people have besides Left ventricular dysfunction? *

  1. Tricuspid Valve Incompetence (inefficient heart valve): 16 people, 51.61%
  2. Mitral Valve Incompetence (inefficient heart valve): 15 people, 48.39%
  3. Hypercoagulation (increased tendency for clotting of the blood): 15 people, 48.39%
  4. Pulmonary Embolism (blockage of the main artery of the lung): 14 people, 45.16%
  5. Ischaemic Cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease): 12 people, 38.71%
  6. Road Traffic Accident: 11 people, 35.48%
  7. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 11 people, 35.48%
  8. Dyslipidaemia (abnormal amount of lipids): 11 people, 35.48%
  9. Muscle Strain (an injury to a muscle in which the muscle fibres tear): 10 people, 32.26%
  10. Pain In Extremity: 10 people, 32.26%

What are the existing conditions these people have? *

  1. Weight Loss: 3 people, 9.68%
  2. Menstrual Disorder (disease of menstrual cycle): 2 people, 6.45%
  3. Uterine Leiomyoma (uterine benign tumour derived from smooth muscle): 1 person, 3.23%
  4. Uterine Haemorrhage (uterine bleeding): 1 person, 3.23%
  5. Pain: 1 person, 3.23%
  6. Migraine (headache): 1 person, 3.23%
  7. Menstruation Irregular: 1 person, 3.23%
  8. Joint Pain: 1 person, 3.23%
  9. Irritable Bowel Syndrome: 1 person, 3.23%
  10. High Blood Pressure: 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Nuvaring and have Left ventricular dysfunction?

- Check whether Left ventricular dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nuvaring:

Left ventricular dysfunction treatments and more:

How severe was Left ventricular dysfunction and when was it recovered:

Expand to all the drugs that have ingredients of ethinyl estradiol; etonogestrel:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nuvaring:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Left ventricular dysfunction:

Browse all the conditions that are associated with Left ventricular dysfunction:

Drugs similar to Nuvaring and Left ventricular dysfunction :


How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; etonogestrel (the active ingredients of Nuvaring) and Nuvaring (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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