Nyquil and Hair loss - a phase IV clinical study of FDA data

Summary:

Hair loss is reported as a side effect among people who take Nyquil (acetaminophen / dextromethorphan / doxylamine / pseudoephedrine), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Tylenol, and have Breast cancer female.

The phase IV clinical study analyzes which people have Hair loss when taking Nyquil. It is created by eHealthMe based on reports of 2,013 people who have side effects when taking Nyquil from the FDA, and is updated regularly.

What is Nyquil?

Nyquil has active ingredients of acetaminophen / dextromethorphan / doxylamine / pseudoephedrine. It is often used in cold symptoms. eHealthMe is studying from 2,240 Nyquil users. Check the latest studies of Nyquil.

What is Hair loss?

Hair loss is found to be associated with 2,410 drugs and 3,511 conditions by eHealthMe. Check the latest studies of Hair loss.

On Apr, 17, 2026

2,013 people reported to have side effects when taking Nyquil.
Among them, 33 people (1.64%) have Hair loss.

Among these 33 people:

How long have people been on Nyquil when they have Hair loss? *

What is the gender of people who have Hair loss when taking Nyquil? *

female: 96.88 %
male: 3.12 %

What is the age of people who have Hair loss when taking Nyquil? *

What are other drugs people take besides Nyquil? *

What are other side effects people have besides Hair loss? *

Fatigue (feeling of tiredness): 6 people, 18.18%
Psychological Trauma: 6 people, 18.18%
Hair Color Changes: 5 people, 15.15%
Hair Texture Abnormal: 5 people, 15.15%
Joint Pain: 5 people, 15.15%
Urinary Tract Infection: 4 people, 12.12%
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 4 people, 12.12%
Hyperkeratosis (thickening of the outer layer of the skin): 4 people, 12.12%
Pain In Extremity: 4 people, 12.12%
Sinusitis (inflammation of sinus): 4 people, 12.12%

What are the existing conditions these people have? *

Breast Cancer Female: 11 people, 33.33%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 18.18%
Drowsiness: 3 people, 9.09%
Breast Cancer: 3 people, 9.09%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 9.09%
Thyroid Cancer: 2 people, 6.06%
Diabetes: 2 people, 6.06%
Stress And Anxiety: 2 people, 6.06%
Renal Cell Carcinoma Stage Iv (stage iv renal cell cancer have cancer that has spread to other organs, such as the lungs, liver, bones, or brain, and may have spread to lymph nodes): 2 people, 6.06%
Hyperthyroidism (over activity of the thyroid gland): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Nyquil and have Hair loss?

- Check whether Hair loss is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nyquil:

Nyquil (2,240 reports)

Hair loss treatments and more:

Hair loss (271,201 reports)

How severe was Hair loss and when was it recovered:

Hair loss in Nyquil

Expand to all the drugs that have ingredients of acetaminophen / dextromethorphan / doxylamine / pseudoephedrine:

Hair loss and drugs with ingredients of acetaminophen / dextromethorphan / doxylamine / pseudoephedrine (35 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nyquil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hair loss:

Hair loss (2,410 drugs)

Browse all the conditions that are associated with Hair loss:

Hair loss (3,511 conditions)

Related publications that referenced our studies

Lindsey SF, Tosti A, "Hair loss induced by tumor necrosis factor alpha inhibitors", J Clin Investigat Dermatol, 2015 Jan .
Lindsey SF, Tosti A, "Hair loss induced by tumor necrosis factor alpha inhibitors", J Clin Investigat Dermatol, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen / dextromethorphan / doxylamine / pseudoephedrine (the active ingredients of Nyquil) and Nyquil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.