Ocaliva and Peripheral coldness - a phase IV clinical study of FDA data

Summary:

Peripheral coldness is reported as a side effect among people who take Ocaliva (obeticholic acid), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Ursodiol,.

The phase IV clinical study analyzes which people have Peripheral coldness when taking Ocaliva. It is created by eHealthMe based on reports of 6,917 people who have side effects when taking Ocaliva from the FDA, and is updated regularly.

What is Ocaliva?

Ocaliva has active ingredients of obeticholic acid. eHealthMe is studying from 6,919 Ocaliva users. Check the latest studies of Ocaliva.

What is Peripheral coldness?

Peripheral coldness is found to be associated with 1,085 drugs and 1,152 conditions by eHealthMe. Check the latest studies of Peripheral coldness.

On Jul, 17, 2026

6,917 people reported to have side effects when taking Ocaliva.
Among them, 12 people (0.17%) have Peripheral coldness.

Could Ocaliva cause Peripheral coldness?

Among these 12 people:

How long have people been on Ocaliva when they have Peripheral coldness? *

What is the gender of people who have Peripheral coldness when taking Ocaliva? *

female: 100 %
male: 0.0 %

What is the age of people who have Peripheral coldness when taking Ocaliva? *

What are other drugs people take besides Ocaliva? *

What are other side effects people have besides Peripheral coldness? *

Itching: 11 people, 91.67%
Weakness: 9 people, 75.00%
Sleep Disorder: 9 people, 75.00%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 9 people, 75.00%
Acute Kidney Failure: 6 people, 50.00%
Renal Impairment (severely reduced kidney function): 3 people, 25.00%
Blood Creatinine Increased: 3 people, 25.00%
Wound: 1 person, 8.33%
Rash Pustular (redness with pustules): 1 person, 8.33%
Quality Of Life Decreased: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Ocaliva and have Peripheral coldness?

- Check whether Peripheral coldness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ocaliva:

Ocaliva (6,919 reports)

Browse all side effects of Ocaliva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peripheral coldness:

Peripheral coldness (1,085 drugs)

Browse all the conditions that are associated with Peripheral coldness:

Peripheral coldness (1,152 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on obeticholic acid (the active ingredients of Ocaliva) and Ocaliva (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.